ZC3H12D

Description		zinc finger CCCH-type containing 12D
Image		No pdb structure
GO Annotations	Cellular Component	P-body Nucleus Nucleoplasm Cytoplasm Cytoplasmic Ribonucleoprotein Granule
	Molecular Function	MRNA Binding Nuclease Activity Endonuclease Activity RNA Endonuclease Activity Protein Binding Zinc Ion Binding Hydrolase Activity Metal Ion Binding
	Biological Process	Negative Regulation Of Cell Growth 3'-UTR-mediated MRNA Destabilization Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways
Drugs
Diseases
GWAS		Asthma ( 32296059) Dupuytren's disease ( 21732829 28886342) Eosinophil count ( 32888494) Eosinophil percentage of white cells ( 32888494)
Novel Interacting Genes		2 novel interacting genes: SYNE1 ZC3H12A
Interacting Genes		2 interacting genes: SYNE1 ZC3H12A
Entrez ID		340152
HPRD ID		19272
Ensembl ID		ENSG00000178199
Uniprot IDs		A2A288
PDB IDs
Enriched GO Terms of Interacting Partners?		P-body Nuclear Matrix Organization Cytoskeleton-nuclear Membrane Anchor Activity Nuclear Matrix Anchoring At Nuclear Membrane Cellular Response To Sodium Arsenite Positive Regulation Of Protein Deubiquitination Cellular Response To Salt Response To Sodium Arsenite Positive Regulation Of MiRNA Catabolic Process Negative Regulation Of Cardiac Muscle Contraction Cellular Response To Ionomycin Meiotic Nuclear Membrane Microtubule Tethering Complex Lamin Binding Regulation Of Protein Deubiquitination Negative Regulation Of Nitric Oxide Biosynthetic Process Negative Regulation Of T-helper 17 Cell Differentiation Cellular Response To Chemokine Rough Endoplasmic Reticulum Membrane Negative Regulation Of Macrophage Activation Host-mediated Suppression Of Viral Genome Replication RNA Stem-loop Binding Negative Regulation Of Striated Muscle Contraction MiRNA Catabolic Process RNA Exonuclease Activity Cellular Response To Arsenic-containing Substance Cellular Response To Ether Negative Regulation Of T-helper 17 Type Immune Response 3'-UTR-mediated MRNA Destabilization Negative Regulation Of Heart Contraction Positive Regulation Of Execution Phase Of Apoptosis Positive Regulation Of Lipid Storage Negative Regulation Of T-helper Cell Differentiation Negative Regulation Of Muscle Contraction Negative Regulation Of Blood Circulation MiRNA Metabolic Process Response To Ether Response To Salt Maintenance Of Protein Location In Nucleus Negative Regulation Of CD4-positive, Alpha-beta T Cell Differentiation Positive Regulation Of P38MAPK Cascade Regulation Of T-helper 17 Cell Differentiation MRNA 3'-UTR AU-rich Region Binding RNA Nuclease Activity Response To Arsenic-containing Substance Negative Regulation Of Alpha-beta T Cell Differentiation Nuclear Outer Membrane Negative Regulation Of Interleukin-1 Beta Production Positive Regulation Of Defense Response To Virus By Host Negative Regulation Of Non-canonical NF-kappaB Signal Transduction Negative Regulation Of Interleukin-1 Production
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