SPOPL

Description		speckle type BTB/POZ protein like
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cul3-RING Ubiquitin Ligase Complex
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Binding Identical Protein Binding
	Biological Process	Protein Ubiquitination Regulation Of Proteolysis Negative Regulation Of Protein Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Pathways		Hedgehog 'on' state
Drugs
Diseases
GWAS		Response to antipsychotic treatment ( 23241943)
Novel Interacting Genes		6 novel interacting genes: ATF2 CREB5 EPS15 KPNA5 MYD88 RXRB
Interacting Genes		6 interacting genes: ATF2 CREB5 EPS15 KPNA5 MYD88 RXRB
Entrez ID		339745
HPRD ID		11261
Ensembl ID		ENSG00000144228
Uniprot IDs		Q6IQ16
PDB IDs
Enriched GO Terms of Interacting Partners?		CAMP Response Element Binding Abducens Nucleus Development MRNA Transcription MRNA Transcription By RNA Polymerase II Hypoglossal Nucleus Development JNK Cascade Establishment Of Protein Localization To Organelle TIR Domain Binding Toll Binding ATP-dependent Histone Chaperone Activity Induced Systemic Resistance Positive Regulation Of Macromolecule Metabolic Process Cellular Response To Anisomycin Growth Plate Cartilage Chondrocyte Differentiation Protein Localization To Organelle Intrinsic Apoptotic Signaling Pathway In Response To Hypoxia Positive Regulation Of Cardiac Muscle Myoblast Proliferation Facial Nucleus Development Histone H2B Acetyltransferase Activity Import Into Nucleus Sequence-specific Double-stranded DNA Binding H4 Histone Acetyltransferase Complex Positive Regulation Of Transforming Growth Factor Beta2 Production Positive Regulation Of DNA-binding Transcription Factor Activity Growth Plate Cartilage Chondrocyte Proliferation DNA-binding Transcription Factor Activity Protein Import Into Nucleus RNA Polymerase II Transcription Regulator Complex Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 8 Signaling Pathway Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Response To Anisomycin NK T Cell Differentiation Detection Of Cell Density Identical Protein Binding Toll-like Receptor TLR6:TLR2 Signaling Pathway Positive Regulation Of Metabolic Process Regulation Of DNA-binding Transcription Factor Activity Protein Localization To Nucleus Positive Regulation Of RNA Metabolic Process Response To Molecule Of Fungal Origin Ubiquitin-dependent Endocytosis Regulation Of Chemokine (C-X-C Motif) Ligand 1 Production Toll-like Receptor Binding Ventricular Cardiac Muscle Cell Differentiation Positive Regulation Of Vitamin D Receptor Signaling Pathway Brainstem Development Positive Regulation Of Nucleobase-containing Compound Metabolic Process Chondrocyte Differentiation Involved In Endochondral Bone Morphogenesis
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