KCNK18

Description		potassium two pore domain channel subfamily K member 18
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane
	Molecular Function	Potassium Channel Activity Calcium-activated Potassium Channel Activity Outward Rectifier Potassium Channel Activity Potassium Ion Leak Channel Activity Metal Ion Binding
	Biological Process	Monoatomic Ion Transport Potassium Ion Transport Regulation Of CD4-positive, CD25-positive, Alpha-beta Regulatory T Cell Differentiation Monoatomic Ion Transmembrane Transport Cellular Response To PH Potassium Ion Transmembrane Transport Potassium Ion Export Across Plasma Membrane
Pathways		TWIK-related spinal cord K+ channel (TRESK) Phase 4 - resting membrane potential
Drugs
Diseases
GWAS		Body mass index ( 26426971)
Novel Interacting Genes		2 novel interacting genes: TGFBR1 TGFBR2
Interacting Genes		2 interacting genes: TGFBR1 TGFBR2
Entrez ID		338567
HPRD ID		17173
Ensembl ID		ENSG00000186795
Uniprot IDs		Q7Z418
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Epithelial To Mesenchymal Transition Involved In Endocardial Cushion Formation Transforming Growth Factor Beta Ligand-receptor Complex Activin Receptor Complex Activin Receptor Activity, Type I Regulation Of Epithelial To Mesenchymal Transition Involved In Endocardial Cushion Formation Transforming Growth Factor Beta Receptor Activity Positive Regulation Of Cardiac Epithelial To Mesenchymal Transition Activin Binding Transmembrane Receptor Protein Serine/threonine Kinase Activity Transforming Growth Factor Beta Binding Response To Cholesterol Embryonic Cranial Skeleton Morphogenesis Activin Receptor Signaling Pathway Ventricular Septum Morphogenesis Positive Regulation Of SMAD Protein Signal Transduction Lens Development In Camera-type Eye SMAD Binding Positive Regulation Of Epithelial To Mesenchymal Transition Artery Morphogenesis Regulation Of SMAD Protein Signal Transduction Cardiac Septum Morphogenesis Roof Of Mouth Development Embryonic Skeletal System Morphogenesis Epithelial To Mesenchymal Transition Regulation Of Stem Cell Proliferation Blood Vessel Morphogenesis Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Mesenchymal Cell Differentiation Regulation Of Epithelial To Mesenchymal Transition Skeletal System Morphogenesis Embryonic Organ Morphogenesis Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway Positive Regulation Of Vasculature Development Cell Proliferation Involved In Endocardial Cushion Morphogenesis Positive Regulation Of Tolerance Induction To Self Antigen Superior Endocardial Cushion Morphogenesis Inferior Endocardial Cushion Morphogenesis Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway Receptor Complex Membrane Raft In Utero Embryonic Development Embryo Development Ending In Birth Or Egg Hatching Multicellular Organism Development Response To Alcohol Chordate Embryonic Development Vascular Endothelial Cell Proliferation Epicardium Morphogenesis Heart Development Bronchus Morphogenesis
Tagcloud ?