RAB7B

Description		RAB7B, member RAS oncogene family
Image		No pdb structure
GO Annotations	Cellular Component	Lysosome Endosome Late Endosome Golgi Apparatus Trans-Golgi Network Membrane Phagocytic Vesicle Membrane Organelle Membrane Cytoplasmic Vesicle Late Endosome Membrane Phagocytic Vesicle
	Molecular Function	Nucleotide Binding GTPase Activity Protein Binding GTP Binding
	Biological Process	Regulation Of Immune System Process Endosome To Lysosome Transport Protein Transport Positive Regulation Of Interleukin-6 Production Negative Regulation Of Toll-like Receptor 4 Signaling Pathway Negative Regulation Of Toll-like Receptor 9 Signaling Pathway Late Endosome To Golgi Transport Positive Regulation Of Megakaryocyte Differentiation Positive Regulation Of NF-kappaB Transcription Factor Activity Cellular Response To Type II Interferon Phagosome-lysosome Fusion
Pathways		TBC/RABGAPs RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS
Novel Interacting Genes		3 novel interacting genes: APP APPBP2 RAP1B
Interacting Genes		3 interacting genes: APP APPBP2 RAP1B
Entrez ID		338382
HPRD ID		15202
Ensembl ID		ENSG00000276600
Uniprot IDs		A0A096LP44 Q96AH8
PDB IDs
Enriched GO Terms of Interacting Partners?		Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Cellular Response To CAMP Response To CAMP Acetylcholine Receptor Activator Activity Membrane Raft PTB Domain Binding Response To Purine-containing Compound Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Positive Regulation Of ERK1 And ERK2 Cascade Regulation Of Cell Junction Assembly Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Regulation Of ERK1 And ERK2 Cascade Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Growth Factor Receptor Binding Main Axon Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Establishment Of Localization In Cell Synapse Organization Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Negative Regulation Of Synaptic Vesicle Exocytosis Axon Choice Point Recognition Heparan Sulfate Binding Signaling Receptor Activator Activity Peptidase Activator Activity Cellular Response To Manganese Ion Negative Regulation Of Calcium Ion-dependent Exocytosis Rap Protein Signal Transduction Antifungal Humoral Response Nuclear Envelope Lumen
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