HOXD11

Description		homeobox D11
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Branching Involved In Ureteric Bud Morphogenesis Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Dorsal/ventral Pattern Formation Embryonic Skeletal Joint Morphogenesis
Pathways		Formation of the ureteric bud
Drugs
Diseases
GWAS		Appendicular lean mass ( 33097823) Creatinine levels ( 31015462) Digit length ratio ( 29659830) Digit length ratio (left hand) ( 29659830) Digit length ratio (right hand) ( 29659830) Haemorrhoidal disease ( 33888516) Heel bone mineral density ( 30598549) Hematocrit ( 27863252 32888494) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) Male-pattern baldness ( 28196072) Red blood cell count ( 32888494)
Novel Interacting Genes		2 novel interacting genes: HMGB1 MEIS1
Interacting Genes		2 interacting genes: HMGB1 MEIS1
Entrez ID		3237
HPRD ID		00869
Ensembl ID		ENSG00000128713
Uniprot IDs		P31277
PDB IDs
Enriched GO Terms of Interacting Partners?		Sensory Organ Development Calcium-dependent Protein Kinase Regulator Activity Regulation Of Restriction Endodeoxyribonuclease Activity Eye Development Positive Regulation Of Myeloid Progenitor Cell Differentiation Regulation Of Myeloid Cell Differentiation Regulation Of Mismatch Repair Negative Regulation Of DNA-templated Transcription Initiation C-X-C Chemokine Binding Alphav-beta3 Integrin-HMGB1 Complex Positive Regulation Of Hematopoietic Progenitor Cell Differentiation Positive Regulation Of Toll-like Receptor 2 Signaling Pathway T-helper 1 Cell Activation Negative Regulation Of RNA Polymerase II Transcription Preinitiation Complex Assembly Positive Regulation Of Mismatch Repair Plasmacytoid Dendritic Cell Activation Positive Regulation Of Toll-like Receptor 9 Signaling Pathway Myeloid Progenitor Cell Differentiation Negative Regulation Of Transcription Initiation By RNA Polymerase II Regulation Of Myeloid Progenitor Cell Differentiation Positive Regulation Of Glycogen Catabolic Process Supercoiled DNA Binding Positive Regulation Of Dendritic Cell Differentiation Regulation Of Endodeoxyribonuclease Activity Negative Regulation Of Apoptotic Cell Clearance Neutrophil Clearance Regulation Of Hemopoiesis DNA Geometric Change Regulation Of Glycogen Catabolic Process Bubble DNA Binding Cell Growth Involved In Cardiac Muscle Cell Development Regulation Of Apoptotic Cell Clearance Positive Regulation Of Chemokine (C-X-C Motif) Ligand 2 Production Regulation Of Toll-like Receptor 9 Signaling Pathway DNA Topological Change Endothelial Cell Chemotaxis RAGE Receptor Binding Regulation Of T Cell Mediated Immune Response To Tumor Cell T-helper 1 Cell Differentiation DNA Binding, Bending Cellular Response To Interleukin-7 Response To Interleukin-7 Positive Regulation Of Monocyte Chemotactic Protein-1 Production Negative Regulation Of Cell Differentiation Regulation Of Dendritic Cell Differentiation Positive Regulation Of Viral Entry Into Host Cell Positive Regulation Of Toll-like Receptor 4 Signaling Pathway Lens Morphogenesis In Camera-type Eye Dendritic Cell Chemotaxis Four-way Junction DNA Binding
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