HOXB7

Description		homeobox B7
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytosol Nuclear Body
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Anterior/posterior Pattern Specification Myeloid Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Embryonic Organ Development Embryonic Skeletal System Morphogenesis Positive Regulation Of Branching Involved In Ureteric Bud Morphogenesis
Pathways
Drugs
Diseases
GWAS		Hypertension ( 27618447) LDL cholesterol levels ( 32203549) Mean arterial pressure ( 30487518) Pulse pressure ( 27618447 28135244) Systolic blood pressure ( 27618447 30487518)
Novel Interacting Genes		13 novel interacting genes: APP CLK3 CREBBP CSNK2A1 EP300 GMNN HOXB6 IRAK3 NFKBIA PARP1 PBX1 PKNOX1 XRCC6
Interacting Genes		13 interacting genes: APP CLK3 CREBBP CSNK2A1 EP300 GMNN HOXB6 IRAK3 NFKBIA PARP1 PBX1 PKNOX1 XRCC6
Entrez ID		3217
HPRD ID		00850
Ensembl ID		ENSG00000260027
Uniprot IDs		P09629
PDB IDs
Enriched GO Terms of Interacting Partners?		Transcription Regulator Complex Regulation Of Innate Immune Response Regulation Of Gene Expression Immune System Process Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Regulation Of Protein Localization To Nucleus Damaged DNA Binding Activation Of Innate Immune Response Regulation Of Macromolecule Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Defense Response Histone H3K27 Acetyltransferase Activity Regulation Of Transcription By RNA Polymerase II Chromatin Binding Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Defense Response Regulation Of RNA Metabolic Process Regulation Of Metabolic Process Histone H3K18 Acetyltransferase Activity N-terminal Peptidyl-lysine Acetylation Peptide Lactyltransferase (CoA-dependent) Activity Positive Regulation Of Innate Immune Response Regulation Of Immune Response Regulation Of Nucleobase-containing Compound Metabolic Process Nucleus Recombinational Repair Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Protein-DNA Complex Negative Regulation Of Biosynthetic Process Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of RNA Biosynthetic Process Cellular Response To Radiation Positive Regulation Of DNA-templated Transcription Hemopoiesis Innate Immune Response-activating Signaling Pathway DNA-binding Transcription Factor Binding Activation Of Immune Response Canonical NF-kappaB Signal Transduction Positive Regulation Of RNA Metabolic Process Response To Radiation Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Metabolic Process Double-strand Break Repair Innate Immune Response Activating Cell Surface Receptor Signaling Pathway
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