HOXB2

Description		homeobox B2
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Morphogenesis Of An Epithelial Sheet Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Nervous System Development Anterior/posterior Pattern Specification Dorsal/ventral Pattern Formation Rhombomere 3 Development Rhombomere 4 Development Facial Nerve Structural Organization Positive Regulation Of Transcription By RNA Polymerase II Embryonic Skeletal System Morphogenesis Skeletal System Morphogenesis Neural Nucleus Development
Pathways		Activation of anterior HOX genes in hindbrain development during early embryogenesis
Drugs
Diseases
GWAS		Body mass index ( 26426971) Experiencing mood swings ( 29500382) Feeling hurt ( 29500382) Keratoconus ( 33649486) Primary tooth development (number of teeth) ( 20195514)
Novel Interacting Genes		13 novel interacting genes: CREBBP DTX2 EP300 MID2 MNDA MORN3 NDOR1 PBX4 RCHY1 RUNX1T1 SOD1 UBASH3B ZNF410
Interacting Genes		13 interacting genes: CREBBP DTX2 EP300 MID2 MNDA MORN3 NDOR1 PBX4 RCHY1 RUNX1T1 SOD1 UBASH3B ZNF410
Entrez ID		3212
HPRD ID		00854
Ensembl ID		ENSG00000173917
Uniprot IDs		P14652
PDB IDs
Enriched GO Terms of Interacting Partners?		Histone H3K18 Acetyltransferase Activity N-terminal Peptidyl-lysine Acetylation Histone H3K27 Acetyltransferase Activity Peptide Lactyltransferase (CoA-dependent) Activity Zinc Ion Binding P53 Binding N-terminal Protein Amino Acid Acetylation Peptidyl-lysine Acetylation Nucleus Regulation Of Cellular Response To Heat Acetyltransferase Activity Cellular Response To Lectin Stimulatory C-type Lectin Receptor Signaling Pathway Transcription Coregulator Activity Histone Acetyltransferase Complex Protein-lysine-acetyltransferase Activity Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Histone Acetyltransferase Activity Protein Acetylation DNA-binding Transcription Factor Binding Phosphoprotein Binding Activation Of Innate Immune Response Tau Protein Binding Transcription Coactivator Binding Immune Response-activating Cell Surface Receptor Signaling Pathway Peptidyl-lysine Propionylation Swimming Histone Lactyltransferase (CoA-dependent) Activity Peptidyl-lysine Butyrylation Peptidyl-lysine Crotonylation Histone H3K122 Acetyltransferase Activity Histone Butyryltransferase Activity Histone Crotonyltransferase Activity NADPH-iron-sulfur [2Fe-2S] Protein Oxidoreductase Activity Protein Destabilization Canonical NF-kappaB Signal Transduction Damaged DNA Binding Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of Cell Activation Transcription Coactivator Activity Positive Regulation Of Innate Immune Response Innate Immune Response Activating Cell Surface Receptor Signaling Pathway Histone H2B Acetyltransferase Activity Acetylation-dependent Protein Binding Peptide Butyryltransferase Activity Peptide 2-hydroxyisobutyryltransferase Activity Protein Propionyltransferase Activity Peptide Crotonyltransferase Activity Response To Antipsychotic Drug Action Potential Initiation
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