HLCS

Description		holocarboxylase synthetase
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nuclear Lamina Cytoplasm Mitochondrion Cytosol Nuclear Matrix
	Molecular Function	Nucleotide Binding Catalytic Activity Biotin--[biotin Carboxyl-carrier Protein] Ligase Activity Protein Binding ATP Binding Biotin Binding Ligase Activity Enzyme Binding Identical Protein Binding
	Biological Process	Biotin Metabolic Process Post-translational Protein Modification Response To Biotin
Pathways		Biotin transport and metabolism Defective HLCS causes multiple carboxylase deficiency
Drugs		Biotin
Diseases		Holocarboxylase synthetase deficiency
GWAS		Developmental language disorder ( 27016271) Developmental language disorder (linguistic errors) ( 27016271) Hematocrit ( 32888494) Hemoglobin ( 32888494) Intracranial aneurysm ( 29531279) Night sleep phenotypes ( 27126917) Red blood cell count ( 32888494) Seasonality and depression ( 30217971)
Novel Interacting Genes		19 novel interacting genes: ACACB ANKRD29 BACH1 DDX52 IFNAR2 IFNGR2 IFT20 KRTAP5-9 LANCL2 MED19 NGB POT1 QKI SARS2 SNX27 SOD1 TGM3 TXNDC15 WIPF1
Interacting Genes		19 interacting genes: ACACB ANKRD29 BACH1 DDX52 IFNAR2 IFNGR2 IFT20 KRTAP5-9 LANCL2 MED19 NGB POT1 QKI SARS2 SNX27 SOD1 TGM3 TXNDC15 WIPF1
Entrez ID		3141
HPRD ID		08360
Ensembl ID		ENSG00000159267
Uniprot IDs		A0A8C8QSB1 P50747
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?