HBG1

Description		hemoglobin subunit gamma 1
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GO Annotations	Cellular Component	Cytosol Hemoglobin Complex Haptoglobin-hemoglobin Complex
	Molecular Function	Oxygen Carrier Activity Oxygen Binding Heme Binding Hemoglobin Alpha Binding Metal Ion Binding
	Biological Process	Carbon Dioxide Transport Oxygen Transport Erythrocyte Development
Pathways		Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Beta thalassemia/hemoglobin E disease ( 20183929) Hematology traits ( 23263863) Hemoglobin levels ( 26366553) Logical memory (delayed recall) in normal cognition ( 29274321) Logical memory (immediate recall) in normal cognition ( 29274321) Malaria ( 31844061) Mean corpuscular hemoglobin concentration ( 23263863)
Novel Interacting Genes		6 novel interacting genes: APP HRAS KRTAP10-3 KRTAP10-9 TRIM54 ZDHHC17
Interacting Genes		6 interacting genes: APP HRAS KRTAP10-3 KRTAP10-9 TRIM54 ZDHHC17
Entrez ID		3047
HPRD ID		00789
Ensembl ID		ENSG00000213934
Uniprot IDs		D9YZU8 P69891
PDB IDs		1I3D 1I3E
Enriched GO Terms of Interacting Partners?		Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Regulation Of Neuronal Synaptic Plasticity Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Long-term Neuronal Synaptic Plasticity Modulation Of Chemical Synaptic Transmission Regulation Of Response To Calcium Ion Regulation Of ERK1 And ERK2 Cascade Regulation Of Type II Interferon Production Regulation Of MiRNA Metabolic Process Amylin Binding Positive Regulation Of JNK Cascade Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Positive Regulation Of Type II Interferon Production Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Glial Cell Development Positive Regulation Of G Protein-coupled Receptor Internalization Regulation Of MAPK Cascade Phospholipase C Activator Activity GTPase Complex Postsynaptic Golgi Apparatus Regulation Of Modification Of Synapse Structure, Modulating Synaptic Transmission Perforant Pathway To Dendrate Granule Cell Synapse Keratin Filament Regulation Of JNK Cascade Axonogenesis Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Norepinephrine Stimulus Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Intermediate Filament Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Defense Response To Other Organism Positive Regulation Of Amyloid Fibril Formation Growth Factor Receptor Binding Main Axon Positive Regulation Of ERK1 And ERK2 Cascade Protein-cysteine S-myristoyltransferase Activity Regulation Of Spontaneous Synaptic Transmission
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