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GUCY2D

Description guanylate cyclase 2D, retinal
Image
GO Annotations Cellular Component
  • Photoreceptor Outer Segment
  • Nuclear Outer Membrane
  • Endoplasmic Reticulum Membrane
  • Plasma Membrane
  • Integral Component Of Plasma Membrane
  • Photoreceptor Outer Segment Membrane
  • Photoreceptor Disc Membrane
Molecular Function
  • Peptide Receptor Activity
  • Guanylate Cyclase Activity
  • Protein Kinase Activity
  • Protein Binding
  • ATP Binding
  • GTP Binding
  • Signaling Receptor Activity
  • Protein Homodimerization Activity
Biological Process
  • CGMP Biosynthetic Process
  • Protein Phosphorylation
  • Signal Transduction
  • Receptor Guanylyl Cyclase Signaling Pathway
  • Visual Perception
  • Regulation Of Rhodopsin Mediated Signaling Pathway
  • Intracellular Signal Transduction
Pathways
  • Inactivation, recovery and regulation of the phototransduction cascade
Drugs
Diseases
  • Leber congenital amaurosis (LCR)
  • Cone-rod dystrophy and cone dystrophy, including: Cone-rod dystrophy (CORD); Cone dystrophy (COD); Retinal cone dystrophy (RCD)
GWAS
  • Refractive error ( 32231278)
Interacting Genes 5 interacting genes: GUCA1A GUCA1B GUCA2B RGS9 S100B
Entrez ID 3000
HPRD ID 02550
Ensembl ID ENSG00000132518
Uniprot IDs Q02846
PDB IDs 1AWL
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025