PSAT1

Description		phosphoserine aminotransferase 1
Image
GO Annotations	Cellular Component	Cytoplasm Cytosol Extracellular Exosome
	Molecular Function	O-phospho-L-serine:2-oxoglutarate Aminotransferase Activity Protein Binding Transaminase Activity Transferase Activity Pyridoxal Phosphate Binding Identical Protein Binding
	Biological Process	L-serine Metabolic Process L-serine Biosynthetic Process Pyridoxine Biosynthetic Process Amino Acid Biosynthetic Process
Pathways		Serine metabolism
Drugs		Pyridoxal phosphate Glutamic acid
Diseases
GWAS		Daytime nap ( 33568662) Metabolite levels ( 23823483) Obesity-related traits ( 23251661) Visceral fat ( 22589738)
Novel Interacting Genes		6 novel interacting genes: APP CDC42 CEBPE DOCK1 MAPK6 PSMD10
Interacting Genes		6 interacting genes: APP CDC42 CEBPE DOCK1 MAPK6 PSMD10
Entrez ID		29968
HPRD ID		17918
Ensembl ID		ENSG00000135069
Uniprot IDs		Q9Y617
PDB IDs		3E77 8A5V 8A5W
Enriched GO Terms of Interacting Partners?		Intracellular Signaling Cassette Endocytosis Regulation Of Postsynapse Organization Import Into Cell Postsynapse Phagocytosis, Engulfment Neuron Projection Organization Intracellular Signal Transduction Regulation Of Synapse Organization Macrophage Differentiation Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Membrane Invagination Positive Regulation Of Cell Cycle Regulation Of Substrate Adhesion-dependent Cell Spreading Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Vesicle-mediated Transport Phagocytosis Integrin-mediated Signaling Pathway Acetylcholine Receptor Activator Activity PTB Domain Binding Regulation Of Growth Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Lipoprotein Particle Positive Regulation Of Locomotion Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Regulation Of MAPK Cascade Endothelin Receptor Signaling Pathway Involved In Heart Process GBD Domain Binding Positive Regulation Of Cell-substrate Adhesion Storage Vacuole Septin Cytoskeleton Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Proteasome Regulatory Particle Assembly Myeloid Leukocyte Differentiation Regulation Of Synapse Assembly Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway
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