DSE

Description		dermatan sulfate epimerase
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GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Membrane Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle
	Molecular Function	Isomerase Activity Metal Ion Binding Chondroitin-glucuronate 5-epimerase Activity
	Biological Process	Heparan Sulfate Proteoglycan Biosynthetic Process Dermatan Sulfate Proteoglycan Biosynthetic Process Chondroitin Sulfate Proteoglycan Metabolic Process Dermatan Sulfate Proteoglycan Metabolic Process
Pathways		DS-GAG biosynthesis
Drugs
Diseases
GWAS		Fast beta electroencephalogram ( 28040410) Height ( 28552196) Heschl's gyrus morphology ( 25130324) Hip circumference adjusted for BMI ( 34021172) Mean platelet volume ( 32888494) Platelet count ( 32888494) Refractive error ( 32231278) Systemic lupus erythematosus ( 33272962 33536424)
Novel Interacting Genes		2 novel interacting genes: ACSL4 INTS11
Interacting Genes		2 interacting genes: ACSL4 INTS11
Entrez ID		29940
HPRD ID		05807
Ensembl ID		ENSG00000111817
Uniprot IDs		A0A2R8YE23 A0A2U3TZJ0 B3KY37 B7Z1T3 B7Z765 Q9UL01
PDB IDs		6HZN
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Prostaglandin Secretion Long-chain Fatty-acyl-CoA Biosynthetic Process Negative Regulation Of Icosanoid Secretion Very Long-chain Fatty Acid-CoA Ligase Activity Long-chain Fatty Acid-CoA Ligase Activity Embryonic Process Involved In Female Pregnancy Alpha-linolenic Acid Metabolic Process Mitochondria-associated Endoplasmic Reticulum Membrane Contact Site Arachidonate-CoA Ligase Activity Nucleobase-containing Compound Biosynthetic Process Negative Regulation Of Fatty Acid Transport Palmitoyl-CoA Ligase Activity SnRNA 3'-end Processing Integrator Complex INTAC Complex RNA Polymerase II Transcription Initiation Surveillance Long-chain Fatty-acyl-CoA Metabolic Process Fatty-acyl-CoA Biosynthetic Process Long-chain Fatty Acid Biosynthetic Process Negative Regulation Of Lipid Transport Regulation Of Fatty Acid Transport Unsaturated Fatty Acid Biosynthetic Process SnRNA Processing Nuclear RNA Surveillance RNA Surveillance RNA Endonuclease Activity Transcription Elongation By RNA Polymerase II Fatty Acid Derivative Biosynthetic Process SnRNA Metabolic Process DNA-templated Transcription Elongation Peroxisomal Membrane Fatty Acid Derivative Metabolic Process Unsaturated Fatty Acid Metabolic Process Lipid Droplet Long-chain Fatty Acid Metabolic Process Acyl-CoA Metabolic Process Positive Regulation Of Insulin Secretion RNA 3'-end Processing Regulation Of Transcription Elongation By RNA Polymerase II Sulfur Compound Biosynthetic Process Regulation Of DNA-templated Transcription Elongation Positive Regulation Of Peptide Hormone Secretion Positive Regulation Of Peptide Secretion Fatty Acid Biosynthetic Process Ligase Activity Blood Microparticle Peroxisome Olefinic Compound Metabolic Process Regulation Of Lipid Transport
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