UBN1

Description		ubinuclein 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Bicellular Tight Junction Nuclear Body PML Body Centriolar Satellite Anchoring Junction
	Molecular Function	DNA Binding Protein Binding
	Biological Process	Chromatin Organization Nucleosome Assembly
Pathways		Formation of Senescence-Associated Heterochromatin Foci (SAHF)
Drugs
Diseases
GWAS		Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean platelet volume ( 32888494) Night sleep phenotypes ( 27126917) Youthful appearance (self-reported) ( 32339537)
Novel Interacting Genes		3 novel interacting genes: H3-3A TJP1 USP7
Interacting Genes		3 interacting genes: H3-3A TJP1 USP7
Entrez ID		29855
HPRD ID		11660
Ensembl ID		ENSG00000118900
Uniprot IDs		Q9NPG3
PDB IDs		4ZBJ
Enriched GO Terms of Interacting Partners?		Regulation Of Centromere Complex Assembly Negative Regulation Of Chromosome Condensation Negative Regulation Of Gene Expression, Epigenetic Protein-containing Complex Pericentric Heterochromatin Formation Barr Body Regulation Of Chromosome Organization Regulation Of Organelle Organization Epigenetic Regulation Of Gene Expression Protein Localization To Bicellular Tight Junction Positive Regulation Of Blood-brain Barrier Permeability Adherens Junction Maintenance Ameloblast Differentiation Protein Localization To Adherens Junction Regulation Of Establishment Of Protein Localization To Chromosome Regulation Of Establishment Of Protein Localization To Telomere Symbiont-mediated Disruption Of Host Cell PML Body Regulation Of Retrograde Transport, Endosome To Golgi Regulation Of Blood-brain Barrier Permeability Monoubiquitinated Protein Deubiquitination Subtelomeric Heterochromatin Formation Positive Regulation Of Cell-cell Adhesion Mediated By Cadherin DNA Alkylation Repair Transcription-coupled Nucleotide-excision Repair Regulation Of Chromosome Condensation Regulation Of Telomere Capping Establishment Of Endothelial Intestinal Barrier Negative Regulation Of Gene Expression Via Chromosomal CpG Island Methylation Cellular Component Assembly Positive Regulation Of Vascular Permeability Organelle Organization Regulation Of Cellular Component Organization Inner Kinetochore Protein Localization To Cell-cell Junction Negative Regulation Of Gluconeogenesis K48-linked Deubiquitinase Activity RNA Polymerase II Core Promoter Sequence-specific DNA Binding Cell-cell Junction Maintenance Regulation Of Bicellular Tight Junction Assembly Oocyte Maturation Chromatin Remodeling Deubiquitinase Activity Chromosome Gap Junction Positive Regulation Of Sprouting Angiogenesis Negative Regulation Of Cellular Component Organization Apical Junction Complex Negative Regulation Of Stress Fiber Assembly Maintenance Of Blood-brain Barrier Negative Regulation Of Actin Filament Bundle Assembly
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