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ORMDL2

Description ORMDL sphingolipid biosynthesis regulator 2
Image No pdb structure
GO Annotations Cellular Component
  • Endoplasmic Reticulum
  • Endoplasmic Reticulum Membrane
  • Membrane
  • Serine Palmitoyltransferase Complex
Molecular Function
  • Protein Binding
Biological Process
  • Sphingolipid Metabolic Process
  • Ceramide Metabolic Process
  • Sphingolipid Biosynthetic Process
  • Intracellular Sphingolipid Homeostasis
  • Negative Regulation Of Ceramide Biosynthetic Process
  • Regulation Of Ceramide Biosynthetic Process
Pathways
  • Sphingolipid de novo biosynthesis
Drugs
Diseases
GWAS
  • Refractive error ( 32231278)
Novel Interacting Genes 28 novel interacting genes: AQP6 BIK CD79A CREB3L1 CYB561 CYB5R3 DAPK1 EBP ELOVL4 ERGIC3 FAM210B FCER1G GJA8 KCNJ6 MMGT1 MTIF3 RETREG3 RNF41 SAR1A SCN3B SLC10A1 SLC35H1 TIMMDC1 TMEM120A TMEM31 TMEM86B TMX2 ZDHHC15
Interacting Genes 28 interacting genes: AQP6 BIK CD79A CREB3L1 CYB561 CYB5R3 DAPK1 EBP ELOVL4 ERGIC3 FAM210B FCER1G GJA8 KCNJ6 MMGT1 MTIF3 RETREG3 RNF41 SAR1A SCN3B SLC10A1 SLC35H1 TIMMDC1 TMEM120A TMEM31 TMEM86B TMX2 ZDHHC15
Entrez ID 29095
HPRD ID 17802
Ensembl ID ENSG00000123353
Uniprot IDs Q53FV1
PDB IDs
Enriched GO Terms of Interacting Partners?
  • Membrane
  • Endoplasmic Reticulum
  • Endoplasmic Reticulum Membrane
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