GPX2

Description		glutathione peroxidase 2
Image
GO Annotations	Cellular Component	Cytoplasm Cytosol Intercellular Bridge Mitotic Spindle
	Molecular Function	Peroxidase Activity Glutathione Peroxidase Activity Electron Transfer Activity Oxidoreductase Activity Phospholipid-hydroperoxide Glutathione Peroxidase Activity
	Biological Process	Response To Oxidative Stress Cellular Oxidant Detoxification
Pathways		Synthesis of 5-eicosatetraenoic acids Synthesis of 12-eicosatetraenoic acid derivatives Synthesis of 15-eicosatetraenoic acid derivatives Detoxification of Reactive Oxygen Species TP53 Regulates Metabolic Genes
Drugs		Glutathione Glutathione Glutathione disulfide Benzoyl peroxide
Diseases
GWAS
Novel Interacting Genes		4 novel interacting genes: MYC PSMB2 SYNE1 TP53
Interacting Genes		4 interacting genes: MYC PSMB2 SYNE1 TP53
Entrez ID		2877
HPRD ID		11818
Ensembl ID		ENSG00000176153
Uniprot IDs		P18283
PDB IDs		2HE3
Enriched GO Terms of Interacting Partners?		Core Promoter Sequence-specific DNA Binding Positive Regulation Of Lymphocyte Apoptotic Process Lymphocyte Apoptotic Process Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Positive Regulation Of Leukocyte Apoptotic Process Negative Regulation Of Fibroblast Proliferation Regulation Of Lymphocyte Apoptotic Process Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Cellular Response To Xenobiotic Stimulus Positive Regulation Of Transcription Initiation By RNA Polymerase II Positive Regulation Of MiRNA Metabolic Process Positive Regulation Of MiRNA Transcription Leukocyte Apoptotic Process T Cell Proliferation Positive Regulation Of DNA-templated Transcription Initiation Regulation Of MiRNA Transcription Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Regulation Of Transcription Initiation By RNA Polymerase II Regulation Of DNA-templated Transcription Initiation Cis-regulatory Region Sequence-specific DNA Binding Cellular Response To Light Stimulus Positive Regulation Of Metanephric Cap Mesenchymal Cell Proliferation Acinar Cell Proliferation Cellular Response To UV Regulation Of MiRNA Metabolic Process Muscle Cell Differentiation Regulation Of Fibroblast Proliferation Regulation Of Telomere Maintenance Positive Regulation Of Acinar Cell Proliferation SCF Ubiquitin Ligase Complex Binding Negative Regulation Of Helicase Activity Negative Regulation Of G1 To G0 Transition Lymphocyte Proliferation Mononuclear Cell Proliferation Regulation Of Signal Transduction By P53 Class Mediator Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Myc-Max Complex Positive Regulation Of Apoptotic Signaling Pathway Leukocyte Proliferation Regulation Of Acinar Cell Proliferation Oligodendrocyte Apoptotic Process Negative Regulation Of Pentose-phosphate Shunt Negative Regulation Of Glucose Catabolic Process To Lactate Via Pyruvate Response To UV Cellular Response To Oxygen Levels NK T Cell Proliferation Cellular Response To Radiation Intrinsic Apoptotic Signaling Pathway Nucleolus
Tagcloud ?