GPT

Description		glutamic--pyruvic transaminase
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytoplasm Cytosol Extracellular Exosome
	Molecular Function	L-alanine:2-oxoglutarate Aminotransferase Activity Transaminase Activity Transferase Activity Pyridoxal Phosphate Binding
	Biological Process	L-alanine Catabolic Process
Pathways		Pyruvate metabolism Alanine metabolism
Drugs		Pyridoxal phosphate Glutamic acid Alanine Phenelzine
Diseases
GWAS		Age at first birth ( 27798627) Alanine aminotransferase levels ( 30718733 33339817) Educational attainment ( 25201988) GLP-1 levels in response to oral glucose tolerance test (fasting) ( 29093273)
Novel Interacting Genes		2 novel interacting genes: CAPN1 CDC7
Interacting Genes		2 interacting genes: CAPN1 CDC7
Entrez ID		2875
HPRD ID		00689
Ensembl ID		ENSG00000167701
Uniprot IDs		P24298
PDB IDs
Enriched GO Terms of Interacting Partners?		NMDA Selective Glutamate Receptor Signaling Pathway Calcium-dependent Cysteine-type Endopeptidase Activity Calpain Complex Self Proteolysis Mammary Gland Involution Double-strand Break Repair Via Break-induced Replication Positive Regulation Of Nuclear Cell Cycle DNA Replication Regulation Of Nuclear Cell Cycle DNA Replication Positive Regulation Of DNA-templated DNA Replication Receptor Catabolic Process Positive Regulation Of Cell Population Proliferation Ionotropic Glutamate Receptor Signaling Pathway Positive Regulation Of Cell Cycle G2/M Phase Transition Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Ligand-gated Ion Channel Signaling Pathway Positive Regulation Of DNA Replication Receptor Metabolic Process Glutamate Receptor Signaling Pathway Cornified Envelope Tissue Remodeling Regulation Of Cell Population Proliferation Cell Cycle G1/S Phase Transition G1/S Transition Of Mitotic Cell Cycle
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