SCAI

Description		suppressor of cancer cell invasion
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Membrane Nuclear Membrane
	Molecular Function	Transcription Corepressor Activity Protein Binding
	Biological Process	DNA-templated Transcription Negative Regulation Of Signal Transduction Negative Regulation Of Cell Migration Negative Regulation Of Rho Protein Signal Transduction Negative Regulation Of DNA-templated Transcription
Pathways		RHO GTPases Activate Formins
Drugs
Diseases
GWAS		Age at first sexual intercourse ( 34211149) Pulse pressure ( 28135244 30578418) Refractive error ( 32231278) Smoking cessation ( 33082346) Worry too long after an embarrassing experience ( 29500382)
Novel Interacting Genes		6 novel interacting genes: CDIPT ITPKB ITSN1 OGT PIN1 SOX7
Interacting Genes		6 interacting genes: CDIPT ITPKB ITSN1 OGT PIN1 SOX7
Entrez ID		286205
HPRD ID		12941
Ensembl ID		ENSG00000173611
Uniprot IDs		Q8N9R8
PDB IDs
Enriched GO Terms of Interacting Partners?		Glycerophospholipid Biosynthetic Process Phosphatidylinositol Metabolic Process Positive Regulation Of Cell Communication Regulation Of Neutrophil Apoptotic Process Phospholipid Biosynthetic Process Regulation Of Small GTPase Mediated Signal Transduction Common Myeloid Progenitor Cell Proliferation Regulation Of Intracellular Signal Transduction Intracellular Signal Transduction Positive Regulation Of Signaling Phosphatidylinositol Biosynthetic Process Inositol Trisphosphate Metabolic Process Inositol-1,4,5-trisphosphate 3-kinase Activity Negative Regulation Of Neutrophil Apoptotic Process Phosphoserine Residue Binding Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Protein Peptidyl-prolyl Isomerization Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Phosphothreonine Residue Binding Glutamatergic Synapse Cis-trans Isomerase Activity Negative Regulation Of Protein Catabolic Process Positive Regulation Of Caveolin-mediated Endocytosis Clathrin-dependent Synaptic Vesicle Endocytosis Regulation Of Caveolin-mediated Endocytosis Regulation Of Modification Of Postsynaptic Actin Cytoskeleton Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Protein N-acetylglucosaminyltransferase Complex Non-canonical Inflammasome Complex Assembly Negative Regulation Of Non-canonical Inflammasome Complex Assembly Positive Regulation Of Transcription By Glucose Carbon Catabolite Regulation Of Transcription Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Protein O-acetylglucosaminyltransferase Activity CDP-diacylglycerol-inositol 3-phosphatidyltransferase Activity Alcohol Binding Inositol Hexakisphosphate Kinase Activity Glycerophospholipid Metabolic Process Postsynaptic Endocytic Zone Positive Regulation Of Growth Hormone Secretion Regulation Of Transcription By Glucose Mitogen-activated Protein Kinase Kinase Binding Postsynaptic Actin Cytoskeleton Positive Thymic T Cell Selection Inositol Phosphate Biosynthetic Process GTPase Activating Protein Binding Ubiquitin Ligase Activator Activity Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway NSL Complex
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