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NKIRAS2
Description
NFKB inhibitor interacting Ras like 2
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Molecular Function
Nucleotide Binding
GTPase Activity
Protein Binding
GTP Binding
GTPase Activating Protein Binding
Biological Process
Inflammatory Response
Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway
Ral Protein Signal Transduction
Regulation Of Canonical NF-kappaB Signal Transduction
Negative Regulation Of Canonical NF-kappaB Signal Transduction
Surfactant Homeostasis
Lung Alveolus Development
Pathways
RIP-mediated NFkB activation via ZBP1
TAK1-dependent IKK and NF-kappa-B activation
TRAF6 mediated NF-kB activation
Drugs
Diseases
GWAS
Novel Interacting Genes
5 novel interacting genes:
NFKBIA
NFKBIB
PAX6
SMN1
TK1
Interacting Genes
5 interacting genes:
NFKBIA
NFKBIB
PAX6
SMN1
TK1
Entrez ID
28511
HPRD ID
07261
Ensembl ID
ENSG00000168256
Uniprot IDs
Q9NYR9
PDB IDs
Enriched GO Terms of Interacting Partners
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Nucleobase-containing Compound Biosynthetic Process
Signal Transduction Involved In Regulation Of Gene Expression
Macromolecule Biosynthetic Process
Forebrain-midbrain Boundary Formation
Pancreatic A Cell Development
I-kappaB/NF-kappaB Complex
Nucleic Acid Metabolic Process
Habenula Development
Pallium Development
DNA Synthesis Involved In Mitotic DNA Replication
Thymidine Kinase Activity
Nucleotide-binding Oligomerization Domain Containing 1 Signaling Pathway
Forebrain Dorsal/ventral Pattern Formation
Regulation Of Asymmetric Cell Division
Oligodendrocyte Cell Fate Specification
Formation Of Anatomical Boundary
Glial Cell Fate Specification
Commitment Of Neuronal Cell To Specific Neuron Type In Forebrain
Cerebral Cortex Regionalization
Lacrimal Gland Development
Telencephalon Regionalization
Thymidine Metabolic Process
Thymidine Biosynthetic Process
Nucleobase-containing Compound Metabolic Process
Forebrain Neuron Fate Commitment
Ventral Spinal Cord Development
Iris Morphogenesis
Response To Molecule Of Bacterial Origin
Response To Lipopolysaccharide
Nucleotide-binding Oligomerization Domain Containing 2 Signaling Pathway
Ubiquitin Protein Ligase Binding
Regulation Of Canonical NF-kappaB Signal Transduction
Negative Regulation Of Macrophage Derived Foam Cell Differentiation
Cytosol
Type B Pancreatic Cell Differentiation
HMG Box Domain Binding
Co-SMAD Binding
Regulation Of Timing Of Cell Differentiation
Cornea Development In Camera-type Eye
Salivary Gland Morphogenesis
Negative Regulation Of Neuroblast Proliferation
SMN Complex
Gemini Of Cajal Bodies
Pyrimidine Nucleoside Metabolic Process
Deoxyribonucleoside Monophosphate Biosynthetic Process
Cellular Response To Cold
Dorsal/ventral Axis Specification
Regulation Of Development, Heterochronic
Embryonic Camera-type Eye Morphogenesis
Enteroendocrine Cell Differentiation
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