SYPL2

Description		synaptophysin like 2
Image		No pdb structure
GO Annotations	Cellular Component	Synaptic Vesicle Membrane Synaptic Vesicle Membrane
	Molecular Function	Protein Binding
	Biological Process	Intracellular Calcium Ion Homeostasis Heart Development Substantia Nigra Development T-tubule Organization
Pathways
Drugs
Diseases
GWAS		Body mass index ( 29273807) Chronic kidney disease ( 20383146) Cognitive ability ( 29186694) Cognitive ability (MTAG) ( 29186694) Estimated glomerular filtration rate ( 31015462 31152163) Glomerular filtration rate (creatinine) ( 26831199 28452372) Major depressive disorder ( 20125088)
Novel Interacting Genes		7 novel interacting genes: ATP13A1 GET3 PLLP SLC38A7 SLC41A1 SNCA YIPF2
Interacting Genes		7 interacting genes: ATP13A1 GET3 PLLP SLC38A7 SLC41A1 SNCA YIPF2
Entrez ID		284612
HPRD ID		17478
Ensembl ID		ENSG00000143028
Uniprot IDs		B4DYR7 Q5VXT5
PDB IDs
Enriched GO Terms of Interacting Partners?		Response To Magnesium Ion Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Monoatomic Ion Transport L-asparagine:sodium Symporter Activity L-glutamine:sodium Symporter Activity Extraction Of Mislocalized Protein From ER Membrane ABC-type Manganese Transporter Activity Membrane Protein Dislocase Activity Inorganic Ion Homeostasis Monoatomic Ion Homeostasis Regulation Of Norepinephrine Uptake Negative Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Positive Regulation Of Hydrogen Peroxide Catabolic Process Monoatomic Cation Homeostasis Regulation Of Transcytosis Magnesium:sodium Antiporter Activity GET Complex Negative Regulation Of Serotonin Uptake Transporter Regulator Activity Negative Regulation Of Chaperone-mediated Autophagy Asparagine Transport L-asparagine Transmembrane Transporter Activity P-type Transmembrane Transporter Activity Metal Ion Transport Negative Regulation Of Dopamine Metabolic Process Regulation Of Serotonin Uptake Compact Myelin P-type Ion Transporter Activity Negative Regulation Of Thrombin-activated Receptor Signaling Pathway Negative Regulation Of Catecholamine Metabolic Process Cellular Response To Metal Ion Dopamine Uptake Involved In Synaptic Transmission Sodium Ion Transport Intracellular Magnesium Ion Homeostasis Cellular Response To Magnesium Ion Monoatomic Cation Transport Establishment Of Protein Localization To Membrane Regulation Of Chaperone-mediated Autophagy Response To Iron(II) Ion Calcium Ion Homeostasis Regulation Of Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Oxidative Phosphorylation Glutamine Transport L-glutamine Transmembrane Transporter Activity Golgi Trans Cisterna Inorganic Cation Transmembrane Transporter Activity
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