GPR22

Description		G protein-coupled receptor 22
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane
	Molecular Function	G Protein-coupled Receptor Activity
	Biological Process	Signal Transduction G Protein-coupled Receptor Signaling Pathway Cell Projection Organization Cellular Response To Hormone Stimulus
Pathways
Drugs
Diseases
GWAS		Liver enzyme levels (alkaline phosphatase) ( 33972514) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Novel Interacting Genes		3 novel interacting genes: CEBPE NFATC4 TFAP2C
Interacting Genes		3 interacting genes: CEBPE NFATC4 TFAP2C
Entrez ID		2845
HPRD ID		03552
Ensembl ID		ENSG00000172209
Uniprot IDs		B3KV13 Q3KNS9 Q99680
PDB IDs
Enriched GO Terms of Interacting Partners?		DNA-templated Transcription Sequence-specific Double-stranded DNA Binding DNA-binding Transcription Factor Activity Nucleobase-containing Compound Biosynthetic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Chromatin DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Positive Regulation Of Transcription By RNA Polymerase II Dichotomous Subdivision Of Terminal Units Involved In Mammary Gland Duct Morphogenesis RNA Metabolic Process Negative Regulation Of Synapse Maturation Morula Formation Macromolecule Biosynthetic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Brain-derived Neurotrophic Factor Receptor Signaling Pathway Transcription By RNA Polymerase II DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Germ-line Stem Cell Population Maintenance Epithelial Cell Proliferation Involved In Mammary Gland Duct Elongation Morphogenesis Of An Epithelium Inner Cell Mass Cell Differentiation Positive Regulation Of RNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Nucleic Acid Metabolic Process Negative Regulation Of Dendrite Morphogenesis Vascular Associated Smooth Muscle Cell Differentiation Sebaceous Gland Development Forebrain Neuron Fate Commitment Tissue Morphogenesis DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Keratinocyte Development Vascular Associated Smooth Muscle Cell Development Cell Differentiation Negative Regulation Of Synapse Organization Cellular Response To Lithium Ion Synapse Maturation Mammary Gland Epithelial Cell Proliferation Regulation Of Transcription By RNA Polymerase II Response To Lithium Ion Nucleobase-containing Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Trophectodermal Cell Differentiation Calcineurin-NFAT Signaling Cascade Positive Regulation Of Biosynthetic Process Cellular Developmental Process Smooth Muscle Cell Differentiation Negative Regulation Of MiRNA Transcription Regulation Of Synapse Maturation
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