EMC10

Description		ER membrane protein complex subunit 10
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GO Annotations	Cellular Component	Extracellular Region Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane EMC Complex
	Molecular Function	Membrane Insertase Activity
	Biological Process	Angiogenesis Positive Regulation Of Endothelial Cell Proliferation Positive Regulation Of Endothelial Cell Migration Protein Insertion Into ER Membrane By Stop-transfer Membrane-anchor Sequence Positive Regulation Of Angiogenesis Tail-anchored Membrane Protein Insertion Into ER Membrane
Pathways
Drugs
Diseases
GWAS		Age-related cognitive decline (memory) (slope of z-scores) ( 30954325)
Novel Interacting Genes		3 novel interacting genes: CCR2 OXTR SMO
Interacting Genes		3 interacting genes: CCR2 OXTR SMO
Entrez ID		284361
HPRD ID		14153
Ensembl ID		ENSG00000161671
Uniprot IDs		Q5UCC4
PDB IDs		6WW7 6Z3W 7ADO 7ADP 8EOI 8J0N 8J0O 8S9S 9C7V
Enriched GO Terms of Interacting Partners?		G Protein-coupled Receptor Activity Homeostasis Of Number Of Cells Within A Tissue Oxytocin Receptor Activity G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cold-induced Thermogenesis Mesenchymal To Epithelial Transition Involved In Metanephric Renal Vesicle Formation Ventral Midline Determination Negative Regulation Of Eosinophil Degranulation Positive Regulation Of Astrocyte Chemotaxis T-helper 17 Cell Chemotaxis Chemokine (C-C Motif) Ligand 12 Binding Chemokine (C-C Motif) Ligand 2 Binding Regulation Of Cold-induced Thermogenesis Tissue Homeostasis Anatomical Structure Homeostasis Homeostasis Of Number Of Cells Positive Regulation Of Immune Complex Clearance By Monocytes And Macrophages Positive Regulation Of Thymocyte Migration Positive Regulation Of CD8-positive, Alpha-beta T Cell Extravasation Chemokine (C-C Motif) Ligand 7 Binding Positive Regulation Of Hematopoietic Stem Cell Migration Regulation Of Astrocyte Chemotaxis Contact Inhibition Pancreas Morphogenesis Regulation Of Thymocyte Migration Regulation Of Immune Complex Clearance By Monocytes And Macrophages Detection Of Cell Density Response To Inositol CCR2 Chemokine Receptor Binding Positive Regulation Of T Cell Extravasation Maternal Process Involved In Parturition Regulation Of Systemic Arterial Blood Pressure By Vasopressin Cerebellar Cortex Morphogenesis Epithelial-mesenchymal Cell Signaling Negative Regulation Of Hair Follicle Development Positive Regulation Of Monocyte Extravasation Monocyte Extravasation Positive Regulation Of Multicellular Organismal Process Neutrophil Clearance Vasopressin Receptor Activity Mesenchymal To Epithelial Transition Involved In Metanephros Morphogenesis Spinal Cord Dorsal/ventral Patterning Midgut Development Patched Binding Cell Surface Receptor Signaling Pathway Determination Of Left/right Asymmetry In Lateral Mesoderm Forebrain Morphogenesis Regulation Of Heart Morphogenesis CAMP-dependent Protein Kinase Inhibitor Activity 9+0 Non-motile Cilium
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