GPM6A

Description		glycoprotein M6A
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Filopodium Axon Growth Cone Cell Projection Neuron Projection Neuronal Cell Body Dendritic Spine Axonal Growth Cone Synapse Presynaptic Active Zone Membrane Extracellular Exosome Parallel Fiber To Purkinje Cell Synapse Presynapse Glutamatergic Synapse Extracellular Vesicle
	Molecular Function	Calcium Channel Activity Protein Binding
	Biological Process	Neuron Migration Neural Retina Development Nervous System Development Synapse Assembly Response To Bacterium Neuron Projection Development Neuron Projection Morphogenesis Stem Cell Differentiation Regulation Of Synapse Organization Positive Regulation Of Filopodium Assembly Calcium Ion Transmembrane Transport
Pathways
Drugs
Diseases
GWAS		Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Cognitive decline rate in late mild cognitive impairment ( 26252872) Educational attainment ( 23722424) Household income (MTAG) ( 31844048) Major depressive disorder x sex interaction ( 34099189) Mortality in heart failure ( 20400778) Schizophrenia ( 25056061 28991256 29483656 30285260) Sensorimotor dexterity ( 31596458) Sepsis (28-day mortality) ( 32592749) Temperament (bipolar disorder) ( 22365631)
Novel Interacting Genes		6 novel interacting genes: CASP3 CEP44 FBXO8 GABARAPL2 PAM16 PRKCA
Interacting Genes		6 interacting genes: CASP3 CEP44 FBXO8 GABARAPL2 PAM16 PRKCA
Entrez ID		2823
HPRD ID		03174
Ensembl ID		ENSG00000150625
Uniprot IDs		P51674
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of ATP-dependent Activity Response To Estradiol Anterior Neural Tube Closure Intrinsic Apoptotic Signaling Pathway In Response To Osmotic Stress Cellular Response To Staurosporine Response To Reactive Oxygen Species Phospholipase A2 Activator Activity Response To Glucocorticoid Response To Corticosteroid Calcium,diacylglycerol-dependent Serine/threonine Kinase Activity Positive Regulation Of Dense Core Granule Biogenesis Positive Regulation Of Angiotensin-activated Signaling Pathway Histone H3T6 Kinase Activity Alphav-beta3 Integrin-PKCalpha Complex Protein Kinase C Signaling Luteolysis Glial Cell Apoptotic Process Regulation Of Angiotensin-activated Signaling Pathway PAM Complex, Tim23 Associated Import Motor Response To Anesthetic Catabolic Process Positive Regulation Of Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Matrix Side Of Mitochondrial Inner Membrane
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