AMT

Description		aminomethyltransferase
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GO Annotations	Cellular Component	Nucleoplasm Mitochondrion Mitochondrial Matrix Glycine Cleavage Complex
	Molecular Function	Aminomethyltransferase Activity Protein Binding Transaminase Activity Transferase Activity
	Biological Process	Glycine Catabolic Process Glycine Decarboxylation Via Glycine Cleavage System
Pathways		Glycine degradation
Drugs		Tetrahydrofolic acid NADH 5-methyltetrahydrofolic acid
Diseases		Nonketotic hyperglycinemia; Glycine encephalopathy (GCE)
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cognitive function ( 25644384) Coronary artery disease ( 29212778) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 28067908) Depressive symptom (depressed mood) (binary trait) ( 31530331) Depressive symptoms (binary sum-score) ( 31530331) Extremely high intelligence ( 29520040) Gut microbiota (functional units) ( 27694959) Inflammatory bowel disease ( 28067908) Regular attendance at a religious group ( 29970889) Sleep duration (short sleep) ( 30846698) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 28067908)
Novel Interacting Genes		8 novel interacting genes: F2RL2 IMPDH2 PDLIM4 RBM15B RHOA SH3BP4 SLMAP VAC14
Interacting Genes		8 interacting genes: F2RL2 IMPDH2 PDLIM4 RBM15B RHOA SH3BP4 SLMAP VAC14
Entrez ID		275
HPRD ID		01997
Ensembl ID		ENSG00000145020
Uniprot IDs		P48728
PDB IDs		1WSR 1WSV
Enriched GO Terms of Interacting Partners?
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