HTATSF1

Description		HIV-1 Tat specific factor 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex U2-type Spliceosomal Complex U2 SnRNP Chromosome Site Of Double-strand Break
	Molecular Function	Nucleic Acid Binding RNA Binding Protein Binding Chromatin-protein Adaptor Activity Poly-ADP-D-ribose Modification-dependent Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome Double-strand Break Repair Via Homologous Recombination DNA Repair Chromatin Organization MRNA Processing DNA Damage Response RNA Splicing U2-type Prespliceosome Assembly Protein Localization To Site Of Double-strand Break
Pathways		mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS
Novel Interacting Genes		22 novel interacting genes: APBB1 CCNT1 CDK9 CLK1 CSNK2A1 ERCC6 FEZ1 GTF2F2 HDAC6 MAP1LC3A POLR2A RNF10 SF3A2 SNRNP70 SNRPB2 SRPK2 SRSF4 SUPT4H1 SUPT5H THAP1 WBP4 ZNF512B
Interacting Genes		22 interacting genes: APBB1 CCNT1 CDK9 CLK1 CSNK2A1 ERCC6 FEZ1 GTF2F2 HDAC6 MAP1LC3A POLR2A RNF10 SF3A2 SNRNP70 SNRPB2 SRPK2 SRSF4 SUPT4H1 SUPT5H THAP1 WBP4 ZNF512B
Entrez ID		27336
HPRD ID		02282
Ensembl ID		ENSG00000102241
Uniprot IDs		O43719
PDB IDs		2DIT 6N3D 6N3E 6N3F 6NSX 6Y50 6Y53 6Y5Q 7EVO 7Q3L 8HK1
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process DNA-templated Transcription Elongation Nucleic Acid Metabolic Process Transcription Elongation By RNA Polymerase II Nucleoplasm Positive Regulation Of DNA-templated Transcription, Elongation Nucleobase-containing Compound Metabolic Process Regulation Of Transcription Elongation By RNA Polymerase II Regulation Of RNA Metabolic Process Regulation Of DNA-templated Transcription Elongation Nucleus Regulation Of Nucleobase-containing Compound Metabolic Process MRNA Metabolic Process Nuclear Speck Regulation Of Gene Expression P-TEFb Complex DSIF Complex Regulation Of Macromolecule Biosynthetic Process Macromolecule Metabolic Process Regulation Of Primary Metabolic Process Regulation Of RNA Splicing Negative Regulation Of DNA-templated Transcription, Elongation RNA Splicing RNA Splicing, Via Transesterification Reactions Negative Regulation Of Nucleobase-containing Compound Metabolic Process Nucleobase-containing Compound Biosynthetic Process Regulation Of Metabolic Process DNA-templated Transcription MRNA Processing Regulation Of Macromolecule Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of MRNA Processing Transcription By RNA Polymerase II Spliceosomal Complex Assembly Transcription Elongation-coupled Chromatin Remodeling U2-type Precatalytic Spliceosome Negative Regulation Of Metabolic Process Cyclin/CDK Positive Transcription Elongation Factor Complex U1 SnRNA Binding Positive Regulation Of Transcription Elongation By RNA Polymerase II 7SK SnRNA Binding Nucleic Acid Binding Positive Regulation Of Metabolic Process Spliceosomal Complex Regulation Of Transcription By RNA Polymerase II Double-strand Break Repair Via Classical Nonhomologous End Joining Regulation Of Autophagy Positive Regulation Of Transcription By RNA Polymerase II SnRNA Binding
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