SMPDL3B

Description		sphingomyelin phosphodiesterase acid like 3B
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Plasma Membrane Membrane Extracellular Exosome Side Of Membrane
	Molecular Function	Sphingomyelin Phosphodiesterase Activity Protein Binding Phosphoric Diester Hydrolase Activity Zinc Ion Binding Hydrolase Activity Hydrolase Activity, Acting On Glycosyl Bonds Metal Ion Binding
	Biological Process	Immune System Process Lipid Metabolic Process Sphingomyelin Catabolic Process Inflammatory Response Lipid Catabolic Process Negative Regulation Of Toll-like Receptor Signaling Pathway Innate Immune Response Membrane Lipid Catabolic Process Negative Regulation Of Inflammatory Response
Pathways
Drugs
Diseases
GWAS
Novel Interacting Genes		2 novel interacting genes: ARID1A OGT
Interacting Genes		2 interacting genes: ARID1A OGT
Entrez ID		27293
HPRD ID		15405
Ensembl ID		ENSG00000130768
Uniprot IDs		B4DEC6 B4DW34 Q92485
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Stem Cell Population Maintenance Regulation Of Stem Cell Population Maintenance Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Non-canonical Inflammasome Complex Assembly Positive Regulation Of Transcription By Glucose Carbon Catabolite Regulation Of Transcription Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Protein O-acetylglucosaminyltransferase Activity Regulation Of Transcription By Glucose BBAF Complex NSL Complex Brahma Complex NpBAF Complex NBAF Complex Nucleosome Disassembly Protein-DNA Complex Disassembly Chromatin Organization Acetylglucosaminyltransferase Activity Sin3-type Complex Regulation Of Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Histone Acetyltransferase Complex Negative Regulation Of Stem Cell Population Maintenance Regulation Of Protein Localization To Synapse Regulation Of Nucleotide-excision Repair Regulation Of Receptor Localization To Synapse SWI/SNF Complex Regulation Of Necroptotic Process Nucleosome Binding Regulation Of Rac Protein Signal Transduction Regulation Of G0 To G1 Transition Phosphatidylinositol-3,4,5-trisphosphate Binding Cellular Response To Nutrient Regulation Of Programmed Necrotic Cell Death Positive Regulation Of Gene Expression, Epigenetic Positive Regulation Of Gene Expression Transcription Initiation-coupled Chromatin Remodeling Nuclear Receptor Binding Positive Regulation Of Developmental Process Positive Regulation Of Myoblast Differentiation Regulation Of Gluconeogenesis Regulation Of Glycolytic Process Negative Regulation Of Translational Initiation Pyroptotic Inflammatory Response Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Translational Initiation Protein-containing Complex Organization Mitophagy Protein Localization To Lysosome
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