IL36A

Description		interleukin 36 alpha
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytoplasm
	Molecular Function	Cytokine Activity Interleukin-1 Receptor Binding Protein Binding
	Biological Process	Positive Regulation Of Cytokine Production Immune System Process Inflammatory Response Immune Response Cytokine-mediated Signaling Pathway Positive Regulation Of Interleukin-6 Production Innate Immune Response Cellular Response To Lipopolysaccharide
Pathways		Interleukin-36 pathway
Drugs
Diseases
GWAS
Novel Interacting Genes		2 novel interacting genes: CFTR TRIM54
Interacting Genes		2 interacting genes: CFTR TRIM54
Entrez ID		27179
HPRD ID		16113
Ensembl ID		ENSG00000136694
Uniprot IDs		Q9UHA7
PDB IDs		6HPI
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Anion Channel Activity Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Positive Regulation Of Monoatomic Anion Transport Positive Regulation Of Enamel Mineralization Positive Regulation Of Tooth Mineralization Chloride Channel Inhibitor Activity Transepithelial Water Transport Chloride Channel Regulator Activity Regulation Of Enamel Mineralization Membrane Hyperpolarization Bicarbonate Transmembrane Transporter Activity Intracellular PH Elevation Amelogenesis ATPase-coupled Inorganic Anion Transmembrane Transporter Activity Regulation Of Monoatomic Anion Transport Epithelial Fluid Transport Golgi-associated Vesicle Membrane Cellular Response To Forskolin Response To Forskolin Chloride Transmembrane Transporter Activity Sperm Capacitation Bicarbonate Transport Water Transport Multicellular Organismal-level Water Homeostasis Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Positive Regulation Of Ion Transmembrane Transporter Activity Cholesterol Biosynthetic Process 14-3-3 Protein Binding Fluid Transport Transepithelial Transport Regulation Of Microtubule Depolymerization Negative Regulation Of Microtubule Depolymerization Microtubule Associated Complex Vesicle Docking Involved In Exocytosis Positive Regulation Of Transporter Activity ABC-type Transporter Activity Sterol Biosynthetic Process Negative Regulation Of Microtubule Polymerization Or Depolymerization Chloride Channel Complex Positive Regulation Of Biomineral Tissue Development Cellular Response To CAMP Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Vesicle Docking Cholesterol Transport Clathrin-coated Endocytic Vesicle Membrane Odontogenesis Of Dentin-containing Tooth Chloride Channel Activity Multicellular Organismal-level Chemical Homeostasis
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