STK36

Description		serine/threonine kinase 36
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleus Cytoplasm Cytosol Cytoskeleton Cell Projection
	Molecular Function	Nucleotide Binding Transcription Corepressor Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Metal Ion Binding Protein Serine Kinase Activity
	Biological Process	Epithelial Cilium Movement Involved In Extracellular Fluid Movement Protein Phosphorylation Microtubule-based Process Smoothened Signaling Pathway Brain Development Post-embryonic Development Cell Projection Organization Axoneme Assembly Positive Regulation Of Smoothened Signaling Pathway Regulation Of DNA-binding Transcription Factor Activity Cilium Assembly
Pathways
Drugs		Fostamatinib
Diseases
GWAS		Amyotrophic lateral sclerosis ( 22959728) Body mass index and triglycerides (pairwise) ( 33619380) Hematocrit ( 27863252) Hemoglobin ( 32888494) Hemoglobin concentration ( 27863252) Hemoglobin levels ( 32327693) Male-pattern baldness ( 28196072) Red blood cell count ( 32888494) Refractive error ( 32231278)
Novel Interacting Genes		12 novel interacting genes: CDK5RAP2 CDK9 CLNK FRMPD4 GLI1 GLI2 GLI3 MAP1LC3B MAST2 MID1 NEIL3 SUFU
Interacting Genes		12 interacting genes: CDK5RAP2 CDK9 CLNK FRMPD4 GLI1 GLI2 GLI3 MAP1LC3B MAST2 MID1 NEIL3 SUFU
Entrez ID		27148
HPRD ID		09631
Ensembl ID		ENSG00000163482
Uniprot IDs		A0A140VJW1 Q9NRP7
PDB IDs
Enriched GO Terms of Interacting Partners?		GLI-SUFU Complex Smoothened Signaling Pathway Involved In Ventral Spinal Cord Interneuron Specification Ciliary Base Spinal Cord Dorsal/ventral Patterning Ciliary Tip Dorsal/ventral Pattern Formation Smoothened Signaling Pathway Smoothened Signaling Pathway Involved In Spinal Cord Motor Neuron Cell Fate Specification Microtubule Binding Proximal/distal Pattern Formation Ventral Midline Development Double-stranded DNA Binding Hindgut Morphogenesis Pattern Specification Process Cerebellar Cortex Morphogenesis Regulation Of Smoothened Signaling Pathway Regionalization Tube Morphogenesis Lung Development Embryonic Digestive Tract Development Axoneme Osteoblast Differentiation Regulation Of Osteoblast Differentiation Pituitary Gland Development Negative Regulation Of Smoothened Signaling Pathway Mammary Gland Development Regulation Of Cell Differentiation Positive Regulation Of DNA Replication Artery Development Cilium Transcription Cis-regulatory Region Binding Notochord Regression Digestive Tract Development Lateral Semicircular Canal Development Sagittal Suture Morphogenesis Lambdoid Suture Morphogenesis Lateral Ganglionic Eminence Cell Proliferation Anterior Semicircular Canal Development Regulation Of Cellular Response To Drug Positive Regulation Of Cellular Response To Drug MCM Complex Binding Gland Development Regulation Of Protein Import Into Nucleus Odontogenesis Of Dentin-containing Tooth Ciliary Basal Body Negative Regulation Of Neuron Differentiation P-TEFb Complex Morphogenesis Of An Epithelium Semicircular Canal Development Mammary Gland Specification
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