CACNG4

Description		calcium voltage-gated channel auxiliary subunit gamma 4
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Voltage-gated Calcium Channel Complex Cell Surface Membrane Endocytic Vesicle Membrane AMPA Glutamate Receptor Complex Monoatomic Ion Channel Complex Somatodendritic Compartment Cell Body Postsynaptic Density Membrane Glutamatergic Synapse L-type Voltage-gated Calcium Channel Complex
	Molecular Function	Voltage-gated Calcium Channel Activity Calcium Channel Regulator Activity Calcium Channel Activity Channel Regulator Activity Ionotropic Glutamate Receptor Binding
	Biological Process	Monoatomic Ion Transport Calcium Ion Transport Transmission Of Nerve Impulse Monoatomic Ion Transmembrane Transport Response To Cocaine Positive Regulation Of Synaptic Transmission, Glutamatergic Calcium Ion Transmembrane Transport Postsynaptic Neurotransmitter Receptor Diffusion Trapping Regulation Of AMPA Receptor Activity
Pathways		Presynaptic depolarization and calcium channel opening Trafficking of AMPA receptors Phase 0 - rapid depolarisation Phase 2 - plateau phase LGI-ADAM interactions
Drugs		Ergocalciferol Enflurane Spironolactone Nicardipine Verapamil Efonidipine Butamben Bioallethrin
Diseases
GWAS		Pursuit maintenance gain ( 29064472) Response to antidepressants (symptom improvement) ( 33589590) SAPHO syndrome ( 33816493) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Novel Interacting Genes		1 novel interacting genes: SPP1
Interacting Genes		1 interacting genes: SPP1
Entrez ID		27092
HPRD ID		05911
Ensembl ID		ENSG00000075461
Uniprot IDs		Q9UBN1
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Positive Regulation Of Estradiol Secretion Regulation Of Estradiol Secretion Positive Regulation Of Bone Resorption Response To Macrophage Colony-stimulating Factor Hormone Catabolic Process Androgen Catabolic Process Negative Regulation Of Collateral Sprouting Negative Regulation Of Axon Regeneration Cellular Response To Testosterone Stimulus Negative Regulation Of Neuron Projection Regeneration Response To 2,3,7,8-tetrachlorodibenzodioxine Regulation Of Collateral Sprouting Decidualization Regulation Of Neuron Projection Regeneration Response To Vitamin D Extracellular Matrix Binding Regulation Of Axon Regeneration Small Molecule Binding Androgen Metabolic Process Steroid Catabolic Process Regulation Of Bone Resorption Embryo Implantation Regulation Of Bone Remodeling Response To Testosterone Negative Regulation Of Axonogenesis Response To Vitamin Regulation Of Tissue Remodeling Positive Regulation Of Lipid Transport Negative Regulation Of Developmental Growth Biomineral Tissue Development Ossification Osteoblast Differentiation Negative Regulation Of Nervous System Development Regulation Of Axonogenesis Integrin Binding Response To Nutrient Regulation Of Lipid Transport Negative Regulation Of Neurogenesis Negative Regulation Of Neuron Projection Development Positive Regulation Of Hormone Secretion Negative Regulation Of Cell Growth Vesicle Regulation Of Response To Wounding Negative Regulation Of Cell Projection Organization Hormone Metabolic Process Cytokine Activity Response To Ketone Response To Steroid Hormone Negative Regulation Of Growth
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