SND1

Description		staphylococcal nuclease and tudor domain containing 1
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GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Membrane RNAi Effector Complex Melanosome Extracellular Exosome Dense Body
	Molecular Function	Nucleic Acid Binding Transcription Coregulator Activity RNA Binding Nuclease Activity Endonuclease Activity RNA Endonuclease Activity Protein Binding Hydrolase Activity Cadherin Binding RISC Complex Binding
	Biological Process	Osteoblast Differentiation MRNA Catabolic Process Regulation Of Cell Cycle Process MiRNA Catabolic Process Regulatory NcRNA-mediated Gene Silencing
Pathways		Signaling by BRAF and RAF1 fusions
Drugs
Diseases
GWAS		Birth weight ( 31043758) Brain morphology (MOSTest) ( 32665545) Cadmium levels ( 26025379) Coffee consumption ( 31046077) Estimated glomerular filtration rate ( 31152163) Fruit consumption ( 32066663) General cognitive ability ( 29844566) General risk tolerance (MTAG) ( 30643258) Haemorrhoidal disease ( 33888516) Hemoglobin A1c levels ( 29403010) Number of sexual partners ( 30643258) Offspring birth weight ( 31043758) Subcortical volume (MOSTest) ( 32665545) Type 2 diabetes ( 23532257 32499647)
Novel Interacting Genes		28 novel interacting genes: APP CEBPA CREBBP CSNK2A1 ESR1 GTF2E1 GTF2E2 HOXA1 LINC00624 LZTR1 MAK MYB MYBL2 PDE4B PIM1 POLR2A PRPF8 PTGER4 RBPJ RNF10 RNU1-1 RNU2-1 RNU4-1 RNU5A-1 RNU6-1 STAT6 SUMO2 UBE2I
Interacting Genes		28 interacting genes: APP CEBPA CREBBP CSNK2A1 ESR1 GTF2E1 GTF2E2 HOXA1 LINC00624 LZTR1 MAK MYB MYBL2 PDE4B PIM1 POLR2A PRPF8 PTGER4 RBPJ RNF10 RNU1-1 RNU2-1 RNU4-1 RNU5A-1 RNU6-1 STAT6 SUMO2 UBE2I
Entrez ID		27044
HPRD ID		03714
Ensembl ID		ENSG00000197157
Uniprot IDs		A0A140VK49 Q7KZF4
PDB IDs		2E6N 2HQE 2HQX 2O4X 3BDL 3OMC 3OMG 4QMG 5M9O 7KNW 7KNX
Enriched GO Terms of Interacting Partners?		Formation Of Quadruple SL/U4/U5/U6 SnRNP Spliceosomal Tri-snRNP Complex Assembly Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of Macromolecule Biosynthetic Process U4/U6 X U5 Tri-snRNP Complex Spliceosomal SnRNP Assembly Positive Regulation Of RNA Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Transcription Factor TFIIE Complex Positive Regulation Of Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Regulation Of RNA Metabolic Process Protein-RNA Complex Assembly Cellular Component Assembly Positive Regulation Of Cell Proliferation Involved In Heart Morphogenesis Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Gene Expression Regulation Of Transcription By RNA Polymerase II Regulation Of Macromolecule Biosynthetic Process Transcription Coactivator Binding Nucleoplasm Negative Regulation Of Transcription By RNA Polymerase II Protein-containing Complex Assembly Cell Activation Involved In Immune Response U6 SnRNA Binding Response To Cytokine Response To Peptide Protein-containing Complex Organization DNA Binding Regulation Of MiRNA Transcription Mammary Gland Epithelial Cell Proliferation Regulation Of Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel Regulation Of Hematopoietic Stem Cell Proliferation Positive Regulation Of Protein Catabolic Process Regulation Of Stem Cell Proliferation Regulation Of Cell Proliferation Involved In Heart Morphogenesis Regulation Of MiRNA Metabolic Process Regulation Of Macromolecule Metabolic Process Transcription Factor Binding SUMO Transferase Activity U5 SnRNP Negative Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Gene Expression Cellular Response To Cytokine Stimulus
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