GJA3

Description		gap junction protein alpha 3
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Gap Junction Connexin Complex Membrane Anchoring Junction
	Molecular Function	Gap Junction Channel Activity Gap Junction Hemi-channel Activity
	Biological Process	Cell Communication Cell-cell Signaling Visual Perception Transmembrane Transport Gap Junction-mediated Intercellular Transport
Pathways		Gap junction assembly
Drugs
Diseases
GWAS		Body fat mass ( 28552196) Facial emotion recognition (happy faces) ( 28608620) Pericalcarine cortex volume ( 31530798)
Novel Interacting Genes		5 novel interacting genes: CAV1 GJA1 MIP PRKCG TJP1
Interacting Genes		5 interacting genes: CAV1 GJA1 MIP PRKCG TJP1
Entrez ID		2700
HPRD ID		00415
Ensembl ID		ENSG00000121743
Uniprot IDs		Q9Y6H8
PDB IDs
Enriched GO Terms of Interacting Partners?		Anatomical Structure Homeostasis Tissue Homeostasis Gap Junction Maintenance Of Blood-brain Barrier Tight Junction Apical Plasma Membrane Anchoring Junction Inward Rectifier Potassium Channel Inhibitor Activity Negative Regulation Of Protein Ubiquitination Homeostatic Process Tissue Remodeling System Process Negative Regulation Of Post-translational Protein Modification Multicellular Organismal-level Homeostasis Positive Regulation Of Cold-induced Thermogenesis Cell-cell Junction Assembly Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Apoptotic Process Plasma Membrane Insulin Receptor Internalization Regulation Of Protein Ubiquitination Protein Localization To Basolateral Plasma Membrane Protein Localization To Plasma Membrane Raft Regulation Of Cold-induced Thermogenesis Intracellular Nitric Oxide Homeostasis Nitric-oxide Synthase Inhibitor Activity Caveolin-mediated Endocytosis Striated Muscle Tissue Development Caveolar Macromolecular Signaling Complex Muscle Tissue Development Negative Regulation Of Pinocytosis Mammary Gland Involution Negative Regulation Of Programmed Cell Death Cellular Response To Hyperoxia Cell-cell Junction Organization Gap Junction Hemi-channel Activity Positive Regulation Of Mesodermal Cell Differentiation Cell Junction Gap Junction Channel Activity Involved In Cardiac Conduction Electrical Coupling Gap Junction Channel Activity Involved In Cell Communication By Electrical Coupling Calmodulin Binding Response To Psychosocial Stress Calcium,diacylglycerol-dependent Serine/threonine Kinase Activity Positive Regulation Of Mismatch Repair Regulation Of Mismatch Repair Positive Regulation Of Blood-brain Barrier Permeability Protein Localization To Adherens Junction Membrane Raft Regulation Of Cellular Component Organization Regulation Of Cell Junction Assembly
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