EHF

Description		ETS homologous factor
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Golgi Apparatus
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Cell Differentiation Epithelial Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		Chronic obstructive pulmonary disease-related biomarkers ( 23144326) Cystic fibrosis severity ( 21602797) Gamma glutamyl transferase levels ( 29403010 33339817) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Lung disease severity in cystic fibrosis ( 26417704) Obesity-related traits ( 23251661) Prostate-specific antigen levels ( 28139693) Response to antipsychotic treatment ( 21107309) Schizophrenia, bipolar disorder or major depressive disorder ( 34099189) Schizophrenia, bipolar disorder or recurrent major depressive disorder ( 34099189) Systemic lupus erythematosus ( 24871463) Systemic lupus erythematosus and Systemic sclerosis ( 23740937) Volumetric brain MRI ( 17903297)
Novel Interacting Genes		4 novel interacting genes: APP FRZB GDF15 TRAF6
Interacting Genes		4 interacting genes: APP FRZB GDF15 TRAF6
Entrez ID		26298
HPRD ID		16105
Ensembl ID		ENSG00000135373
Uniprot IDs		Q9NZC4
PDB IDs
Enriched GO Terms of Interacting Partners?		Amyloid-beta Complex Response To Interleukin-1 Growth Cone Lamellipodium Regulation Of Growth Regulation Of Response To Calcium Ion Regulation Of Multicellular Organism Growth Positive Regulation Of MAPK Cascade Positive Regulation Of Interleukin-6 Production Amylin Binding Positive Regulation Of JNK Cascade Negative Regulation Of Signaling Positive Regulation Of Toll Signaling Pathway Negative Regulation Of Signal Transduction Cell Surface Receptor Signaling Pathway Positive Regulation Of Developmental Process Negative Regulation Of Cell Communication Regulation Of MAPK Cascade Negative Regulation Of Hepatocyte Differentiation Response To Metformin Acetylcholine Receptor Activator Activity Negative Regulation Of Canonical Wnt Signaling Pathway Regulation Of JNK Cascade Regulation Of Developmental Process Regulation Of Interleukin-6 Production Cell Development Positive Regulation Of Small Molecule Metabolic Process Lipoprotein Particle Positive Regulation Of Cell Differentiation Myeloid Leukocyte Activation Positive Regulation Of Protein Import PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Negative Regulation Of Wnt Signaling Pathway Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Regulation Of Leukocyte Migration Regulation Of Signal Transduction Axon Midline Choice Point Recognition Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Positive Regulation Of Intracellular Signal Transduction
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