PLA2G2D

Description		phospholipase A2 group IID
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region
	Molecular Function	Phospholipase A2 Activity Calcium Ion Binding Phospholipid Binding Heparin Binding Hydrolase Activity Heparan Sulfate Proteoglycan Binding Metal Ion Binding Calcium-dependent Phospholipase A2 Activity
	Biological Process	CD4-positive, CD25-positive, Alpha-beta Regulatory T Cell Differentiation Regulation Of Acute Inflammatory Response To Antigenic Stimulus Lipid Metabolic Process Phospholipid Metabolic Process Inflammatory Response Lipid Catabolic Process Negative Regulation Of T Cell Proliferation Phosphatidylethanolamine Metabolic Process Phosphatidylcholine Metabolic Process Phosphatidylglycerol Metabolic Process Arachidonate Secretion Negative Regulation Of T Cell Activation
Pathways		Acyl chain remodelling of PC Acyl chain remodelling of PS Acyl chain remodelling of PE Acyl chain remodelling of PI Acyl chain remodelling of PG Synthesis of PA
Drugs		Lauric acid Stearic acid
Diseases
GWAS		Crohn's disease ( 32581322) Group IIA secretory phospholipase A2 levels in individuals with elevated hsCRP ( 31070471) Obesity-related traits ( 23251661)
Novel Interacting Genes		1 novel interacting genes: ADRB2
Interacting Genes		1 interacting genes: ADRB2
Entrez ID		26279
HPRD ID		07546
Ensembl ID		ENSG00000117215
Uniprot IDs		Q9UNK4
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Systemic Arterial Blood Pressure By Norepinephrine-epinephrine Positive Regulation Of Mini Excitatory Postsynaptic Potential Response To Psychosocial Stress Norepinephrine-epinephrine-mediated Vasodilation Involved In Regulation Of Systemic Arterial Blood Pressure Beta-adrenergic Receptor Activity Norepinephrine Binding Positive Regulation Of Lipophagy AMPA Selective Glutamate Receptor Signaling Pathway Beta2-adrenergic Receptor Activity Positive Regulation Of Autophagosome Maturation Heat Generation Adrenergic Receptor Activity Diet Induced Thermogenesis Adenylate Cyclase Binding Negative Regulation Of Smooth Muscle Contraction Negative Regulation Of Multicellular Organism Growth Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Regulation Of Autophagosome Maturation Positive Regulation Of CAMP/PKA Signal Transduction Negative Regulation Of Muscle Contraction Neuronal Dense Core Vesicle Adrenergic Receptor Signaling Pathway Negative Regulation Of Systemic Arterial Blood Pressure Adaptive Thermogenesis Bone Resorption Regulation Of Systemic Arterial Blood Pressure Mediated By A Chemical Signal Brown Fat Cell Differentiation Ionotropic Glutamate Receptor Signaling Pathway Positive Regulation Of Excitatory Postsynaptic Potential Temperature Homeostasis Positive Regulation Of Protein-containing Complex Disassembly Regulation Of CAMP/PKA Signal Transduction Potassium Channel Regulator Activity Ligand-gated Ion Channel Signaling Pathway Regulation Of Systemic Arterial Blood Pressure Response To Cold Positive Regulation Of Bone Mineralization Glutamate Receptor Signaling Pathway Cellular Response To Amyloid-beta Modulation Of Excitatory Postsynaptic Potential Negative Regulation Of Blood Pressure Positive Regulation Of Biomineral Tissue Development Smooth Muscle Contraction Vasodilation Negative Regulation Of G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Ossification Endosome To Lysosome Transport Regulation Of Smooth Muscle Contraction Response To Amyloid-beta Regulation Of Multicellular Organism Growth
Tagcloud ?