FBXO6

Description		F-box protein 6
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol SCF Ubiquitin Ligase Complex Endoplasmic Reticulum Quality Control Compartment
	Molecular Function	Protein Binding Carbohydrate Binding Ubiquitin Protein Ligase Activity
	Biological Process	DNA Damage Checkpoint Signaling DNA Repair Proteolysis Ubiquitin-dependent Protein Catabolic Process Glycoprotein Catabolic Process DNA Damage Response Response To Unfolded Protein Protein Ubiquitination SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process ERAD Pathway
Pathways		Association of TriC/CCT with target proteins during biosynthesis Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Arterial stiffness (brachial-femoral pulse wave velocity) ( 32790701)
Novel Interacting Genes		3 novel interacting genes: ORC4 RIOK1 SKP1
Interacting Genes		3 interacting genes: ORC4 RIOK1 SKP1
Entrez ID		26270
HPRD ID		07291
Ensembl ID		ENSG00000116663
Uniprot IDs		Q9NRD1
PDB IDs
Enriched GO Terms of Interacting Partners?		Nuclear Origin Of Replication Recognition Complex Meiotic Cytokinesis Origin Recognition Complex Polar Body Extrusion After Meiotic Divisions F-box Domain Binding Cul7-RING Ubiquitin Ligase Complex Ubiquitin Ligase Complex Scaffold Activity Positive Regulation Of RRNA Processing Methyltransferase Complex Ubiquitin Ligase Activator Activity Preribosome, Small Subunit Precursor Regulation Of RRNA Processing DNA Replication Origin Binding DNA Replication Initiation Maintenance Of Protein Location In Nucleus PcG Protein Complex Cullin Family Protein Binding Molecular Function Activator Activity Positive Regulation Of Epithelial Cell Apoptotic Process Maturation Of SSU-rRNA Maintenance Of Protein Localization In Organelle
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