CLEC4E

Description		C-type lectin domain family 4 member E
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GO Annotations	Cellular Component	Phagocytic Cup Plasma Membrane External Side Of Plasma Membrane Membrane Phagocytic Vesicle Membrane Cell Projection
	Molecular Function	Calcium Ion Binding Protein Binding Carbohydrate Binding Signaling Receptor Activity Pattern Recognition Receptor Activity Metal Ion Binding Glycolipid Binding
	Biological Process	Positive Regulation Of Cytokine Production Pattern Recognition Receptor Signaling Pathway T Cell Differentiation Involved In Immune Response Immune System Process Immune Response-regulating Signaling Pathway Immune Response Fc-gamma Receptor Signaling Pathway Defense Response To Bacterium Innate Immune Response Antifungal Innate Immune Response
Pathways		Dectin-2 family Dectin-2 family
Drugs		Cholesterol
Diseases
GWAS		Takayasu arteritis ( 25604533)
Novel Interacting Genes		4 novel interacting genes: CXCL9 FAM3C FCER1G NKG7
Interacting Genes		4 interacting genes: CXCL9 FAM3C FCER1G NKG7
Entrez ID		26253
HPRD ID		13075
Ensembl ID		ENSG00000166523
Uniprot IDs		F5H5X7 Q9ULY5
PDB IDs		3WH2 3WH3
Enriched GO Terms of Interacting Partners?		Granulocyte Migration Defense Response Neutrophil Chemotaxis Myeloid Leukocyte Migration IgE Receptor Activity Regulated Exocytosis Defense Response To Other Organism Leukocyte Degranulation Granulocyte Chemotaxis Neutrophil Migration Lymphocyte Mediated Immunity Defense Response To Symbiont Inflammatory Response Killing Of Cells Of Another Organism Natural Killer Cell Mediated Cytotoxicity Directed Against Tumor Cell Target Leukocyte Chemotaxis Positive Regulation Of Type I Hypersensitivity Leukocyte Mediated Immunity Myeloid Leukocyte Differentiation Fc-epsilon Receptor I Complex Negative Regulation Of Mast Cell Apoptotic Process Serotonin Secretion By Platelet Fc-gamma Receptor III Complex Positive Regulation Of Inflammatory Response Positive Regulation Of Type III Hypersensitivity Cell Killing Cell Chemotaxis Mast Cell Apoptotic Process Serotonin Secretion Positive Regulation Of Type IIa Hypersensitivity Exocytosis Cytokine Activity Cytolytic Granule Membrane Response To Other Organism Leukocyte Migration Response To Stress Positive Regulation Of Mast Cell Cytokine Production IgE Binding Regulation Of Mast Cell Apoptotic Process CXCR3 Chemokine Receptor Binding Immune Response Myeloid Cell Differentiation Positive Regulation Of Hypersensitivity Interleukin-3-mediated Signaling Pathway Natural Killer Cell Degranulation Immune Response To Tumor Cell Response To External Biotic Stimulus Positive Regulation Of Acute Inflammatory Response To Antigenic Stimulus Mast Cell Activation T Cell Activation
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