INTS1

Description		integrator complex subunit 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Membrane Nuclear Membrane Integrator Complex INTAC Complex
	Molecular Function	Protein Binding
	Biological Process	Blastocyst Growth Inner Cell Mass Cell Proliferation Embryo Implantation SnRNA Processing Regulation Of Transcription Elongation By RNA Polymerase II U2 SnRNA 3'-end Processing Negative Regulation Of Apoptotic Process RNA Polymerase II Transcription Initiation Surveillance
Pathways		RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes
Drugs
Diseases
GWAS		Executive inhibition (Stroop WIT and CIT) in attention deficit hyperactivity disorder ( 28416812)
Novel Interacting Genes		5 novel interacting genes: CTDP1 DEAF1 DNAAF5 MTNR1B RNF10
Interacting Genes		5 interacting genes: CTDP1 DEAF1 DNAAF5 MTNR1B RNF10
Entrez ID		26173
HPRD ID		10899
Ensembl ID		ENSG00000164880
Uniprot IDs		Q8N201
PDB IDs		7CUN 7PKS 7YCX 8RBX 8RBZ 8RC4 8YJB
Enriched GO Terms of Interacting Partners?		Melatonin Receptor Activity Positive Regulation Of Transmission Of Nerve Impulse Positive Regulation Of Circadian Sleep/wake Cycle, Sleep Negative Regulation Of CGMP-mediated Signaling Regulation Of Nervous System Process Regulation Of Neuronal Action Potential Negative Regulation Of Transmission Of Nerve Impulse Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Regulation Of System Process Positive Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep TFIIF-class Transcription Factor Complex Binding RNA Polymerase II CTD Heptapeptide Repeat Phosphatase Activity Postsynapse To Nucleus Signaling Pathway Extrinsic Component Of Postsynaptic Density Membrane Negative Regulation Of Schwann Cell Proliferation
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