RGS22

Description		regulator of G protein signaling 22
Image		No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Nucleus Cytoplasm Cytosol Actin Cytoskeleton
	Molecular Function	G-protein Alpha-subunit Binding
	Biological Process	Regulation Of Signal Transduction Negative Regulation Of Signal Transduction
Pathways		G alpha (i) signalling events
Drugs
Diseases
GWAS		Basal cell carcinoma ( 24403052 25855136 27539887 33549134) Non-melanoma skin cancer ( 29739929)
Novel Interacting Genes		1 novel interacting genes: FBXO7
Interacting Genes		1 interacting genes: FBXO7
Entrez ID		26166
HPRD ID		13155
Ensembl ID		ENSG00000132554
Uniprot IDs		G3V112 Q8NE09
PDB IDs
Enriched GO Terms of Interacting Partners?		Glial Cytoplasmic Inclusion Classical Lewy Body Lewy Body Corona Lewy Neurite Lewy Body Core Negative Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Mitophagy Positive Regulation Of Autophagy Of Mitochondrion Protein Targeting To Mitochondrion Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Mitophagy Establishment Of Protein Localization To Mitochondrion Negative Regulation Of Cell Cycle G1/S Phase Transition Negative Regulation Of Lymphocyte Differentiation Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Autophagy Of Mitochondrion Autophagy Of Mitochondrion SCF Ubiquitin Ligase Complex Ubiquitin-like Ligase-substrate Adaptor Activity Ubiquitin Ligase Complex Positive Regulation Of Macroautophagy Protein K48-linked Ubiquitination Negative Regulation Of Intrinsic Apoptotic Signaling Pathway Ubiquitin Binding Negative Regulation Of Hemopoiesis Negative Regulation Of Lymphocyte Activation Negative Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Autophagy Negative Regulation Of Neuron Apoptotic Process Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Negative Regulation Of Cell Activation Protein Targeting Regulation Of Lymphocyte Differentiation Negative Regulation Of Cell Cycle Phase Transition Negative Regulation Of Mitotic Cell Cycle Regulation Of Intrinsic Apoptotic Signaling Pathway Regulation Of Macroautophagy Negative Regulation Of Leukocyte Activation Negative Regulation Of Apoptotic Signaling Pathway Regulation Of Neuron Apoptotic Process Lymphocyte Differentiation Ubiquitin-protein Transferase Activity
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