RWDD3

Description		RWD domain containing 3
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm
	Molecular Function	Protein Binding
	Biological Process	Negative Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of Protein Sumoylation Positive Regulation Of Hypoxia-inducible Factor-1alpha Signaling Pathway
Pathways		SUMO is transferred from E1 to E2 (UBE2I, UBC9)
Drugs
Diseases
GWAS		Alcohol consumption (drinks per week) ( 30679032) Caffeine consumption from coffee ( 33287642) Chronotype ( 30696823) Daytime nap ( 33568662) Motion sickness ( 25628336) Palmitic acid (16:0) levels ( 23362303) Platelet distribution width ( 27863252) Smoking status (ever vs never smokers) ( 30643258) Stearic acid (18:0) levels ( 23362303) Verbal declarative memory ( 25648963)
Novel Interacting Genes		4 novel interacting genes: HIF1A NFKBIA UBE2I VHL
Interacting Genes		4 interacting genes: HIF1A NFKBIA UBE2I VHL
Entrez ID		25950
HPRD ID		11527
Ensembl ID		ENSG00000122481
Uniprot IDs		Q9Y3V2
PDB IDs		2EBK 4Y1L
Enriched GO Terms of Interacting Partners?		Enzyme Binding Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of TOR Signaling Regulation Of Cytokine Production Involved In Inflammatory Response Regulation Of Intracellular Signal Transduction SUMO Conjugating Enzyme Activity Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Cellular Response To Decreased Oxygen Levels Cellular Response To Hypoxia Negative Regulation Of Intracellular Signal Transduction Regulation Of Transcription By RNA Polymerase II Cellular Response To Oxygen Levels Regulation Of TOR Signaling Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process Neural Fold Elevation Formation Positive Regulation Of Chemokine-mediated Signaling Pathway Negative Regulation Of Transcription By RNA Polymerase II I-kappaB/NF-kappaB Complex RING-like Zinc Finger Domain Binding Elastin Metabolic Process Epithelial Cell Differentiation Involved In Mammary Gland Alveolus Development Negative Regulation Of Gene Expression Regulation Of DNA-templated Transcription Regulation Of Myeloid Cell Differentiation Hypoxia-inducible Factor-1alpha Signaling Pathway Regulation Of Signal Transduction Regulation Of RNA Biosynthetic Process B-1 B Cell Homeostasis Intestinal Epithelial Cell Maturation Connective Tissue Replacement Involved In Inflammatory Response Wound Healing SUMO Ligase Complex Small Protein Activating Enzyme Binding HLH Domain Binding Intracellular Transport Nuclear Transport Nucleocytoplasmic Transport Hemoglobin Biosynthetic Process Vascular Endothelial Growth Factor Production Nucleotide-binding Oligomerization Domain Containing 1 Signaling Pathway Glandular Epithelial Cell Maturation Regulation Of RNA Metabolic Process Regulation Of Cell Communication Regulation Of Signaling Nucleoplasm Mesenchymal Cell Apoptotic Process
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