CNOT10

Description		CCR4-NOT transcription complex subunit 10
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GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Membrane CCR4-NOT Complex
	Molecular Function	Protein Binding
	Biological Process	Nuclear-transcribed MRNA Poly(A) Tail Shortening MRNA Catabolic Process Regulation Of Translation Negative Regulation Of Translation Regulatory NcRNA-mediated Gene Silencing
Pathways		Deadenylation of mRNA TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain M-decay: degradation of maternal mRNAs by maternally stored factors
Drugs
Diseases
GWAS		Diabetic retinopathy in type 2 diabetes ( 33607655) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Sensorimotor dexterity ( 31596458)
Novel Interacting Genes		4 novel interacting genes: CHMP1B LTB4R2 OBI1 RNF10
Interacting Genes		4 interacting genes: CHMP1B LTB4R2 OBI1 RNF10
Entrez ID		25904
HPRD ID		16731
Ensembl ID		ENSG00000182973
Uniprot IDs		Q9H9A5
PDB IDs		8BFI 8FY3
Enriched GO Terms of Interacting Partners?		Protein Autoubiquitination Protein Monoubiquitination Ubiquitin Protein Ligase Activity Ribosome-associated Ubiquitin-dependent Protein Catabolic Process Postsynapse To Nucleus Signaling Pathway Negative Regulation Of Schwann Cell Proliferation Extrinsic Component Of Postsynaptic Density Membrane Leukotriene Signaling Pathway Keratinocyte Migration Negative Regulation Of Adenylate Cyclase Activity Leukotriene B4 Receptor Activity Leukotriene Receptor Activity ESCRT III Complex MIT Domain Binding Amphisome Membrane Vesicle Fusion With Vacuole ESCRT III Complex Disassembly ESCRT Complex Disassembly Viral Budding From Plasma Membrane Lysosomal Membrane Organization Multivesicular Body-lysosome Fusion Modification-dependent Protein Catabolic Process Positive Regulation Of Myelination Negative Regulation Of Glial Cell Proliferation Ubiquitin-dependent Protein Catabolic Process Plasma Membrane Repair Mitotic Cytokinetic Process Multivesicular Body Membrane Late Endosome To Lysosome Transport Kinetochore Microtubule Viral Budding Nuclear Membrane Reassembly Viral Budding Via Host ESCRT Complex Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of Mitotic Spindle Assembly Viral Release From Host Cell Midbody Abscission Membrane Coat Protein Ubiquitination Multivesicular Body Organization Multivesicular Body Assembly Regulation Of Spindle Assembly Epithelial Cell Migration Regulation Of Glial Cell Proliferation Negative Regulation Of Gliogenesis Proteolysis Involved In Protein Catabolic Process Protein Modification By Small Protein Conjugation G Protein-coupled Peptide Receptor Activity Regulation Of Mitotic Spindle Organization Late Endosome To Vacuole Transport
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