RNF19A

Description		ring finger protein 19A, RBR E3 ubiquitin protein ligase
Image		No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Cytoplasm Centrosome Cytosol Cytoskeleton Membrane
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Transferase Activity Ubiquitin Conjugating Enzyme Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Microtubule Cytoskeleton Organization Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination
Pathways		Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Amyotrophic lateral sclerosis (sporadic) ( 24529757) Atrioventricular conduction ( 21041692) Recurrent major depressive disorder ( 29317602)
Novel Interacting Genes		17 novel interacting genes: C11orf58 CASR ILK MAP3K20 MAP3K7 NUDT21 RPS6KA5 SNCAIP SOD1 SUFU TUBG1 TUBG2 UBE2D2 UBE2E2 UBE2L3 UBE2L6 VCP
Interacting Genes		17 interacting genes: C11orf58 CASR ILK MAP3K20 MAP3K7 NUDT21 RPS6KA5 SNCAIP SOD1 SUFU TUBG1 TUBG2 UBE2D2 UBE2E2 UBE2L3 UBE2L6 VCP
Entrez ID		25897
HPRD ID		06176
Ensembl ID		ENSG00000034677
Uniprot IDs		Q9NV58
PDB IDs
Enriched GO Terms of Interacting Partners?		Ubiquitin Conjugating Enzyme Activity Nucleotide Binding Microtubule Nucleator Activity Mitotic Spindle Organization ISG15 Transferase Activity Microtubule Cytoskeleton Organization Involved In Mitosis ISG15-protein Conjugation Spindle Organization ATP Binding JNK Cascade Magnesium Ion Binding Gamma-tubulin Ring Complex Gamma-tubulin Complex Protein Modification Process Ubiquitin-protein Transferase Activity Post-translational Protein Modification Nucleus Ubiquitin Protein Ligase Binding Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Protein Polyubiquitination Ubiquitin-like Protein Transferase Activity Stress-activated MAPK Cascade MAP Kinase Kinase Kinase Activity Meiotic Spindle Organization Pericentriolar Material Cytoskeleton Organization Protein Ubiquitination P38MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Interleukin-1-mediated Signaling Pathway Chromosome Segregation Proteolysis Involved In Protein Catabolic Process Microtubule Nucleation Protein Exit From Endoplasmic Reticulum Protein Modification By Small Protein Conjugation Positive Regulation Of Intracellular Signal Transduction Protein Serine/threonine Kinase Activity Negative Regulation Of Smoothened Signaling Pathway Mitotic Sister Chromatid Segregation Sister Chromatid Segregation Protein K11-linked Ubiquitination Protein Kinase Binding Identical Protein Binding Microtubule Cytoskeleton Organization Microtubule-based Process Transferase Activity Spindle Microtubule Flavin Adenine Dinucleotide Catabolic Process Histone H2AS1 Kinase Activity
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