SUMF2

Description		sulfatase modifying factor 2
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GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Lumen
	Molecular Function	Protein Binding Identical Protein Binding Metal Ion Binding
	Biological Process
Pathways		The activation of arylsulfatases Glycosphingolipid catabolism
Drugs
Diseases
GWAS		Macular telangiectasia type 2 ( 33654266) Plasma free amino acid levels ( 30659259) Plasma free amino acid levels (adjusted for twenty other PFAAs) ( 30659259)
Novel Interacting Genes		4 novel interacting genes: CACNA1A FBXW7 ZDHHC17 ZFYVE9
Interacting Genes		4 interacting genes: CACNA1A FBXW7 ZDHHC17 ZFYVE9
Entrez ID		25870
HPRD ID		06400
Ensembl ID		ENSG00000129103
Uniprot IDs		A8MXB9 C9J660 Q8NBJ7
PDB IDs		1Y4J
Enriched GO Terms of Interacting Partners?		Protein-cysteine S-myristoyltransferase Activity Postsynaptic Golgi Apparatus Regulation Of Modification Of Synapse Structure, Modulating Synaptic Transmission Perforant Pathway To Dendrate Granule Cell Synapse Parkin-FBXW7-Cul1 Ubiquitin Ligase Complex Negative Regulation Of Hepatocyte Proliferation Ubiquitin Recycling Phosphothreonine Residue Binding Negative Regulation Of SREBP Signaling Pathway Negative Regulation Of Triglyceride Biosynthetic Process Negative Regulation Of Osteoclast Development Positive Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Protein-cysteine S-stearoyltransferase Activity Regulation Of ERK1 And ERK2 Cascade Ubiquitin-protein Transferase Activator Activity Positive Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Osteoclast Development Regulation Of SREBP Signaling Pathway Regulation Of Neurotrophin TRK Receptor Signaling Pathway
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