NPNT

Description		nephronectin
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Basement Membrane Membrane Smooth Muscle Contractile Fiber Extracellular Matrix Extracellular Exosome
	Molecular Function	Integrin Binding Extracellular Matrix Structural Constituent Calcium Ion Binding
	Biological Process	Ureteric Bud Development Branching Involved In Ureteric Bud Morphogenesis Cell Adhesion Cell-matrix Adhesion Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Cell-substrate Adhesion Cell Differentiation Extracellular Matrix Organization Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Cell-cell Adhesion Mediated By Integrin Establishment Of Protein Localization Positive Regulation Of Osteoblast Differentiation Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Smooth Muscle Contraction Smooth Muscle Cell Differentiation Positive Regulation Of ERK1 And ERK2 Cascade Cellular Response To Tumor Necrosis Factor Pilomotor Reflex
Pathways		Formation of the nephric duct Formation of the ureteric bud
Drugs
Diseases
GWAS		Asthma ( 31959851) Blood protein levels ( 30072576) Chronic obstructive pulmonary disease ( 30804561 28166215) Copper levels ( 26025379) Diastolic blood pressure ( 27841878) FEV1 ( 30804560) Hypertension ( 30487518) Lung function (FEV1) ( 26635082 28166213) Lung function (FEV1/FVC) ( 28166213 30804560 26635082) Lung function (FVC) ( 28166213 30804560) Lung function (low FEV1 vs high FEV1) ( 26423011) Lung function in heavy smokers (low FEV1 vs high FEV1) ( 26423011) Lung function in never smokers (low FEV1 vs high FEV1) ( 26423011) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Medication use (calcium channel blockers) ( 31015401) Medication use (diuretics) ( 31015401) Night sleep phenotypes ( 27126917) Peak expiratory flow ( 30804560) Post bronchodilator FEV1 ( 26634245) Post bronchodilator FEV1/FVC ratio ( 26634245) Pulmonary function ( 20010835) Pulmonary function (smoking interaction) ( 23284291) Pulse pressure ( 30487518 27841878) Systolic blood pressure ( 30578418 28739976 28135244 27841878)
Novel Interacting Genes		1 novel interacting genes: ITGA8
Interacting Genes		1 interacting genes: ITGA8
Entrez ID		255743
HPRD ID		14141
Ensembl ID		ENSG00000168743
Uniprot IDs		Q6UXI9
PDB IDs
Enriched GO Terms of Interacting Partners?		Integrin Alpha8-beta1 Complex Smooth Muscle Cell Differentiation Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Dendritic Spine Membrane Integrin Complex Mesodermal Cell Differentiation Smooth Muscle Tissue Development Metanephros Development Substrate Adhesion-dependent Cell Spreading Formation Of Primary Germ Layer Inner Ear Morphogenesis Postsynaptic Density Membrane Muscle Cell Differentiation Apical Part Of Cell Transforming Growth Factor Beta Receptor Signaling Pathway Cell-matrix Adhesion Positive Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Integrin-mediated Signaling Pathway Memory Perikaryon Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Muscle Tissue Development Cell-substrate Adhesion Kidney Development Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway Extracellular Matrix Organization Extracellular Structure Organization
Tagcloud ?