TAC4

Description		tachykinin precursor 4
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space
	Molecular Function	Substance P Receptor Binding Substance K Receptor Binding Receptor Ligand Activity
	Biological Process	Negative Regulation Of Systemic Arterial Blood Pressure Inflammatory Response Positive Regulation Of Cytosolic Calcium Ion Concentration Tachykinin Receptor Signaling Pathway Regulation Of Blood Pressure Detection Of Temperature Stimulus Involved In Sensory Perception Of Pain Regulation Of Sensory Perception Of Pain Positive Regulation Of Flagellated Sperm Motility Negative Regulation Of Sensory Perception Of Pain Positive Regulation Of Sensory Perception Of Pain
Pathways
Drugs
Diseases
GWAS		Femur bone mineral density x serum urate levels interaction ( 34046847) Serum alkaline phosphatase levels ( 33547301)
Novel Interacting Genes		3 novel interacting genes: TACR1 TACR2 TACR3
Interacting Genes		3 interacting genes: TACR1 TACR2 TACR3
Entrez ID		255061
HPRD ID		09701
Ensembl ID		ENSG00000176358
Uniprot IDs		Q86UU9
PDB IDs		2MOC
Enriched GO Terms of Interacting Partners?		Tachykinin Receptor Activity Positive Regulation Of Uterine Smooth Muscle Contraction Tachykinin Receptor Signaling Pathway Regulation Of Uterine Smooth Muscle Contraction Positive Regulation Of Flagellated Sperm Motility Positive Regulation Of Cilium Movement Regulation Of Flagellated Sperm Motility Positive Regulation Of Smooth Muscle Contraction Regulation Of Cilium Movement Positive Regulation Of Muscle Contraction Sperm Midpiece Regulation Of Microtubule-based Movement Regulation Of Smooth Muscle Contraction Positive Regulation Of Reproductive Process Operant Conditioning Positive Regulation Of Synaptic Transmission, Cholinergic Regulation Of Muscle Contraction Sperm Head Regulation Of Reproductive Process Positive Regulation Of Vascular Permeability Regulation Of Muscle System Process Regulation Of Microtubule-based Process Positive Regulation Of Blood Pressure G Protein-coupled Receptor Activity Response To Electrical Stimulus Regulation Of Vascular Permeability Smooth Muscle Contraction Regulation Of System Process Positive Regulation Of Cell Motility Positive Regulation Of Locomotion G Protein-coupled Receptor Signaling Pathway Response To Estradiol Sperm Flagellum Substance K Receptor Activity Substance P Receptor Activity Regulation Of Cell Motility Positive Regulation Of Synaptic Transmission Regulation Of Locomotion Learning Regulation Of Blood Pressure Angiotensin-mediated Drinking Behavior Muscle Contraction Prolactin Secretion Negative Regulation Of Luteinizing Hormone Secretion Positive Regulation Of Acetylcholine Secretion, Neurotransmission Smooth Muscle Contraction Involved In Micturition Regulation Of Hormone Secretion Regulation Of Acetylcholine Secretion, Neurotransmission Muscle System Process Intestine Smooth Muscle Contraction
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