ACKR1

Description		atypical chemokine receptor 1 (Duffy blood group)
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GO Annotations	Cellular Component	Endosome Early Endosome Plasma Membrane Membrane Recycling Endosome
	Molecular Function	Transmembrane Signaling Receptor Activity G Protein-coupled Receptor Activity Protein Binding Chemokine Binding C-C Chemokine Binding Signaling Receptor Activity
	Biological Process	Defense Response Inflammatory Response Signal Transduction G Protein-coupled Receptor Signaling Pathway Chemokine-mediated Signaling Pathway
Pathways		Peptide ligand-binding receptors
Drugs
Diseases
GWAS		Eotaxin levels ( 27989323) Growth-regulated protein alpha levels ( 27989323) Midgestational total 25-hydroxyvitamin D levels (fetal genetic effect) ( 32047095) Monocyte chemoattractant protein-1 levels ( 27989323 31217265) Neutrophil level response to clozapine in treatment-resistant schizophrenia ( 30647433)
Novel Interacting Genes		10 novel interacting genes: CCL17 CCL2 CCL5 CCL7 CCL8 CD48 CXCL1 CXCL5 CXCL8 MTNR1B
Interacting Genes		10 interacting genes: CCL17 CCL2 CCL5 CCL7 CCL8 CD48 CXCL1 CXCL5 CXCL8 MTNR1B
Entrez ID		2532
HPRD ID		00192
Ensembl ID		ENSG00000213088
Uniprot IDs		Q16570 Q5Y7A1 Q5Y7A2
PDB IDs		4NUU 4NUV 7P93 8A44 8JPS
Enriched GO Terms of Interacting Partners?		Chemokine Activity Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Antimicrobial Humoral Response Cell Chemotaxis Cytokine Activity Humoral Immune Response Chemotaxis Locomotion Granulocyte Chemotaxis Granulocyte Migration Myeloid Leukocyte Migration Inflammatory Response Leukocyte Chemotaxis Eosinophil Chemotaxis Immune Response Eosinophil Migration Defense Response To Symbiont Defense Response To Other Organism Defense Response CCR Chemokine Receptor Binding Leukocyte Migration Cell Migration Cell Motility Positive Regulation Of Leukocyte Migration Response To Other Organism Immune System Process Response To External Biotic Stimulus G Protein-coupled Receptor Signaling Pathway Extracellular Region Regulation Of Leukocyte Migration Chemokine-mediated Signaling Pathway Extracellular Space Positive Regulation Of Leukocyte Chemotaxis Monocyte Chemotaxis Regulation Of Lymphocyte Chemotaxis Cell-cell Signaling Signaling Killing Of Cells Of Another Organism Cellular Response To Fibroblast Growth Factor Stimulus Cell Communication Signal Transduction Positive Regulation Of Chemotaxis Response To Fibroblast Growth Factor CCR2 Chemokine Receptor Binding Response To Stress Cell Killing Cellular Response To Interleukin-1 Regulation Of Granulocyte Chemotaxis Positive Regulation Of Natural Killer Cell Chemotaxis Regulation Of Chemotaxis
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