PHLDA3

Description		pleckstrin homology like domain family A member 3
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Membrane
	Molecular Function	Phosphatidylinositol-4,5-bisphosphate Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Phosphatidylinositol-5-phosphate Binding Phosphatidylinositol-3-phosphate Binding Phosphatidylinositol-3,4-bisphosphate Binding Phosphatidylinositol-3,5-bisphosphate Binding Phosphatidylinositol Phosphate Binding
	Biological Process	Apoptotic Process Anatomical Structure Morphogenesis Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Positive Regulation Of Apoptotic Process Negative Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction
Pathways
Drugs
Diseases
GWAS		Breast cancer ( 29059683)
Novel Interacting Genes		2 novel interacting genes: APP CDK2
Interacting Genes		2 interacting genes: APP CDK2
Entrez ID		23612
HPRD ID		09519
Ensembl ID		ENSG00000174307
Uniprot IDs		Q9Y5J5
PDB IDs
Enriched GO Terms of Interacting Partners?		Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Response To Calcium Ion Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Positive Regulation Of Chromatin Organization Y Chromosome Positive Regulation Of Heterochromatin Formation Cyclin A1-CDK2 Complex Cyclin-dependent Protein Kinase Activity Cyclin A2-CDK2 Complex Cyclin E1-CDK2 Complex Cyclin E2-CDK2 Complex Positive Regulation Of DNA-templated DNA Replication Initiation Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Norepinephrine Stimulus Regulation Of Protein Catabolic Process Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling X Chromosome Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Regulation Of Proteolysis Positive Regulation Of Amyloid Fibril Formation Growth Factor Receptor Binding Main Axon Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Regulation Of Anaphase-promoting Complex-dependent Catabolic Process Histone Kinase Activity Axon Choice Point Recognition Protection From Non-homologous End Joining At Telomere Regulation Of Mitotic Cell Cycle Heparan Sulfate Binding Signaling Receptor Activator Activity
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