ZNF281

Description		zinc finger protein 281
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm
	Molecular Function	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Sequence-specific DNA Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Embryonic Body Morphogenesis Negative Regulation Of Gene Expression Cell Differentiation Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription Stem Cell Differentiation
Pathways
Drugs
Diseases
GWAS		Antisaccade task score ( 31596458) Myopia ( 27182965) Neurofibrillary tangles ( 31497858) Prepulse inhibition of the startle response ( 31596458) Refractive error ( 32231278)
Novel Interacting Genes		7 novel interacting genes: CD247 EGLN1 FBXW11 MYC PIK3R3 STAT3 ZBTB16
Interacting Genes		7 interacting genes: CD247 EGLN1 FBXW11 MYC PIK3R3 STAT3 ZBTB16
Entrez ID		23528
HPRD ID		11702
Ensembl ID		ENSG00000162702
Uniprot IDs		B3KMX4 Q9Y2X9
PDB IDs
Enriched GO Terms of Interacting Partners?		Cell Surface Receptor Signaling Pathway T Cell Activation Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of RNA Biosynthetic Process Response To Oxygen Levels Positive Regulation Of Metanephric Cap Mesenchymal Cell Proliferation Acinar Cell Proliferation Regulation Of Myeloid Cell Differentiation Regulation Of MiRNA Transcription Intracellular Iron Ion Homeostasis Negative Regulation Of Intracellular Signal Transduction Response To Decreased Oxygen Levels Positive Regulation Of RNA Metabolic Process Positive Regulation Of Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Response To Hypoxia Positive Regulation Of MiRNA Metabolic Process Positive Regulation Of MiRNA Transcription Protein Dimerization Activity Positive Regulation Of Acinar Cell Proliferation Positive Regulation Of DNA-templated Transcription SCF Ubiquitin Ligase Complex Binding Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Cellular Response To Hypoxia Regulation Of Hemopoiesis DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Regulation Of MiRNA Metabolic Process Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Alpha-beta T Cell Activation Lymphocyte Activation Negative Regulation Of Myeloid Cell Differentiation Myc-Max Complex Regulation Of Acinar Cell Proliferation Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Canonical NF-kappaB Signal Transduction Positive Regulation Of Growth Factor Dependent Skeletal Muscle Satellite Cell Proliferation Type 2 Angiotensin Receptor Binding Peptidyl-proline Dioxygenase Activity Negative Regulation Of Hypoxia-inducible Factor-1alpha Signaling Pathway Leukocyte Activation Fc-gamma Receptor III Complex Gamma-delta T Cell Receptor Complex NK T Cell Proliferation Regulation Of Cellular Response To Stress Negative Regulation Of Primary MiRNA Processing Negative Regulation Of Hydrogen Peroxide Biosynthetic Process Positive Regulation Of Skeletal Muscle Cell Proliferation Male Germ-line Stem Cell Asymmetric Division Regulation Protein Catabolic Process At Postsynapse
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