SEC11A

Description		SEC11 homolog A, signal peptidase complex subunit
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GO Annotations	Cellular Component	Endoplasmic Reticulum Signal Peptidase Complex Endoplasmic Reticulum Membrane Membrane
	Molecular Function	Serine-type Endopeptidase Activity Protein Binding Peptidase Activity Hydrolase Activity
	Biological Process	Signal Peptide Processing Proteolysis Response To Virus
Pathways		SRP-dependent cotranslational protein targeting to membrane Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) Synthesis, secretion, and deacylation of Ghrelin Regulation of CDH1 posttranslational processing and trafficking to plasma membrane Maturation of hRSV A proteins
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Hip circumference adjusted for BMI ( 34021172) Response to ketamine in bipolar disorder or major depression (antidepressant effects) ( 30552317) Schizophrenia ( 29483656)
Novel Interacting Genes		10 novel interacting genes: AGBL1 CCL3 CCNDBP1 CEP76 KLHL25 LINC00052 OAZ2 PDE8A PDIA3 RAB27B
Interacting Genes		5 interacting genes: ADAM33 BCHE CSNK2B NUPR1 SLC35F6
Entrez ID		23478
HPRD ID		07503
Ensembl ID		ENSG00000140612
Uniprot IDs		H0YKT4 P67812
PDB IDs		7P2P
Enriched GO Terms of Interacting Partners?
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