SEC11A

Description		SEC11 homolog A, signal peptidase complex subunit
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GO Annotations	Cellular Component	Endoplasmic Reticulum Signal Peptidase Complex Endoplasmic Reticulum Membrane Membrane
	Molecular Function	Serine-type Endopeptidase Activity Protein Binding Peptidase Activity Hydrolase Activity
	Biological Process	Signal Peptide Processing Proteolysis Response To Virus
Pathways		SRP-dependent cotranslational protein targeting to membrane Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) Synthesis, secretion, and deacylation of Ghrelin Regulation of CDH1 posttranslational processing and trafficking to plasma membrane Maturation of hRSV A proteins
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Hip circumference adjusted for BMI ( 34021172) Response to ketamine in bipolar disorder or major depression (antidepressant effects) ( 30552317) Schizophrenia ( 29483656)
Novel Interacting Genes		15 novel interacting genes: ADAM33 AGBL1 BCHE CCL3 CCNDBP1 CEP76 CSNK2B KLHL25 LINC00052 NUPR1 OAZ2 PDE8A PDIA3 RAB27B SLC35F6
Interacting Genes		15 interacting genes: ADAM33 AGBL1 BCHE CCL3 CCNDBP1 CEP76 CSNK2B KLHL25 LINC00052 NUPR1 OAZ2 PDE8A PDIA3 RAB27B SLC35F6
Entrez ID		23478
HPRD ID		07503
Ensembl ID		ENSG00000140612
Uniprot IDs		H0YKT4 P67812
PDB IDs		7P2P
Enriched GO Terms of Interacting Partners?
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