TRAM1

Description		translocation associated membrane protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane
	Molecular Function	Protein Binding Signaling Receptor Activity
	Biological Process	Cotranslational Protein Targeting To Membrane SRP-dependent Cotranslational Protein Targeting To Membrane, Translocation Response To Unfolded Protein Protein Transport Protein Insertion Into ER Membrane
Pathways		SRP-dependent cotranslational protein targeting to membrane
Drugs
Diseases
GWAS		Cardiac Troponin-T levels ( 23247143) Erythrocyte cadmium concentration in never smokers ( 27005419) Refractive error ( 32231278) Spherical equivalent or myopia (age of diagnosis) ( 29808027)
Novel Interacting Genes		13 novel interacting genes: APP CREB3 DRD2 ESR1 ESR2 GUCA2A SEC61B TCF20 TICAM1 TIRAP TRAF6 UBC VKORC1
Interacting Genes		13 interacting genes: APP CREB3 DRD2 ESR1 ESR2 GUCA2A SEC61B TCF20 TICAM1 TIRAP TRAF6 UBC VKORC1
Entrez ID		23471
HPRD ID		05545
Ensembl ID		ENSG00000067167
Uniprot IDs		G3XAN4 Q15629 Q6FHL3
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Interleukin-6 Production Regulation Of Innate Immune Response Cellular Response To Oxygen-containing Compound Positive Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Interleukin-6 Production Positive Regulation Of Nitric Oxide Metabolic Process Nuclear Estrogen Receptor Activity Toll-like Receptor 4 Signaling Pathway Cell Surface Toll-like Receptor Signaling Pathway Toll-like Receptor Signaling Pathway Cell Surface Pattern Recognition Receptor Signaling Pathway Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Nitric Oxide Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Lipid Response To Lipid Regulation Of Defense Response Positive Regulation Of Chemokine Production Positive Regulation Of Biosynthetic Process Intracellular Receptor Signaling Pathway Innate Immune Response Activating Cell Surface Receptor Signaling Pathway Positive Regulation Of Cytokine Production Signaling Adaptor Activity Estrogen Response Element Binding TRIF-dependent Toll-like Receptor Signaling Pathway Regulation Of Immune Response Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Positive Regulation Of Leukocyte Chemotaxis MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Regulation Of Chemokine Production Positive Regulation Of JNK Cascade Regulation Of Immune System Process MyD88-dependent Toll-like Receptor Signaling Pathway Positive Regulation Of Tumor Necrosis Factor Production Positive Regulation Of Macromolecule Metabolic Process Regulation Of Cell Population Proliferation Positive Regulation Of Tumor Necrosis Factor Superfamily Cytokine Production Response To Estradiol Positive Regulation Of DNA-binding Transcription Factor Activity Regulation Of Canonical NF-kappaB Signal Transduction Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Regulation Of Neurotransmitter Uptake Myeloid Leukocyte Activation Regulation Of Type I Interferon Production Nuclear Steroid Receptor Activity Intracellular Signal Transduction Positive Regulation Of Long-term Synaptic Potentiation
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