ARHGEF18

Description		Rho/Rac guanine nucleotide exchange factor 18
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Cytoskeleton Plasma Membrane Apical Plasma Membrane Cell Junction Apical Part Of Cell Extracellular Exosome
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding Metal Ion Binding
	Biological Process	Transforming Growth Factor Beta Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Small GTPase Mediated Signal Transduction Regulation Of Cell Shape Actin Cytoskeleton Organization Regulation Of Rho Protein Signal Transduction Positive Regulation Of Apoptotic Process Regulation Of Catalytic Activity Regulation Of Small GTPase Mediated Signal Transduction Negative Regulation Of Stress Fiber Assembly Protein Localization To Cell-cell Junction
Pathways		NRAGE signals death through JNK Rho GTPase cycle TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) G alpha (12/13) signalling events
Drugs
Diseases
GWAS
Interacting Genes		3 interacting genes: GNB1 HRAS RHOA
Entrez ID		23370
HPRD ID		12479
Ensembl ID		ENSG00000104880
Uniprot IDs		A0A087WZG4 Q6ZSZ5
PDB IDs
Enriched GO Terms of Interacting Partners?
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