USP24

Description		ubiquitin specific peptidase 24
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol
	Molecular Function	Cysteine-type Deubiquitinase Activity Protein Binding Peptidase Activity Cysteine-type Peptidase Activity Hydrolase Activity
	Biological Process	Proteolysis Protein Deubiquitination Regulation Of Protein Stability
Pathways		Ub-specific processing proteases
Drugs
Diseases
GWAS		Airway responsiveness in chronic obstructive pulmonary disease ( 25514360) LDL levels x fish oil supplementation interaction (2df) ( 33760818) Metabolite levels ( 22916037) Methadone dose in opioid dependence ( 28115739) Total cholesterol levels x fish oil supplementation interaction (2df) ( 33760818) Waist-to-hip ratio adjusted for BMI ( 28552196)
Novel Interacting Genes		6 novel interacting genes: CSNK2A1 DDB2 JUNB RUNX2 TP53 UBC
Interacting Genes		6 interacting genes: CSNK2A1 DDB2 JUNB RUNX2 TP53 UBC
Entrez ID		23358
HPRD ID		11664
Ensembl ID		ENSG00000162402
Uniprot IDs		Q9UPU5
PDB IDs
Enriched GO Terms of Interacting Partners?		Transcription Regulator Complex Leukocyte Differentiation Ligamentous Ossification Osteoblast Differentiation Tissue Development Nucleoplasm Stem Cell Proliferation Regulation Of Stem Cell Proliferation Stem Cell Differentiation Regulation Of Cell Population Proliferation Osteoblast Fate Commitment T Cell Differentiation Chromatin DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Cis-regulatory Region Sequence-specific DNA Binding Cell Population Proliferation Negative Regulation Of DNA Metabolic Process Negative Regulation Of Proteolysis Protein Kinase CK2 Complex Cellular Response To Stress Symbiont-mediated Disruption Of Host Cell PML Body Macroautophagy DNA Repair Regulation Of Signal Transduction By P53 Class Mediator Signal Transduction In Response To DNA Damage DNA Damage Checkpoint Signaling PML Body Nucleotide-excision Repair Response To UV Cellular Response To UV Cellular Response To Light Stimulus Leukocyte Proliferation Embryonic Organ Development Oligodendrocyte Apoptotic Process Negative Regulation Of Fermentation Intrinsic Apoptotic Signaling Pathway In Response To Hypoxia Negative Regulation Of Pentose-phosphate Shunt Positive Regulation Of Thymocyte Apoptotic Process Response To Actinomycin D T Cell Proliferation Involved In Immune Response Negative Regulation Of Helicase Activity Oxidative Stress-induced Premature Senescence Negative Regulation Of Glucose Catabolic Process To Lactate Via Pyruvate Negative Regulation Of G1 To G0 Transition Glucose Catabolic Process To Lactate Via Pyruvate Germ Cell Nucleus Cellular Response To Actinomycin D Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway Intracellular Signal Transduction
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