DDHD2

Description		DDHD domain containing 2
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Cytosol Membrane COPII-coated ER To Golgi Transport Vesicle Centriolar Satellite
	Molecular Function	Phospholipase Activity Triacylglycerol Lipase Activity Hydrolase Activity Metal Ion Binding Diacylglycerol Lipase Activity
	Biological Process	Mitochondrial Fission Lipid Metabolic Process Locomotory Behavior Visual Learning Lipid Catabolic Process Triglyceride Catabolic Process Lipid Droplet Organization Positive Regulation Of Mitochondrial Fission
Pathways		Synthesis of PA
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Schizophrenia ( 28991256 29483656)
Novel Interacting Genes		3 novel interacting genes: APP MTNR1A PLAT
Interacting Genes		3 interacting genes: APP MTNR1A PLAT
Entrez ID		23259
HPRD ID		16788
Ensembl ID		ENSG00000085788
Uniprot IDs		B3KPM6 O94830
PDB IDs
Enriched GO Terms of Interacting Partners?		Mating Behavior Reproductive Behavior Acetylcholine Receptor Activator Activity Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Regulation Of Response To Calcium Ion Axon Midline Choice Point Recognition Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Amyloid Fibril Formation Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Lipoprotein Particle Growth Factor Receptor Binding Main Axon Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Receptor Complex Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Low-density Lipoprotein Particle Mediated Signaling Melatonin Receptor Activity Trans-synaptic Signaling By BDNF, Modulating Synaptic Transmission Prevention Of Polyspermy Trans-synaptic Signaling By BDNF Serine Protease Inhibitor Complex Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Trans-synaptic Signaling Axon Choice Point Recognition Synaptic Signaling Negative Regulation Of Plasminogen Activation Heparan Sulfate Binding Signaling Receptor Activator Activity Regulation Of Proteolysis Signaling Receptor Binding Peptidase Activator Activity
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